| 1 | LLY | Eli Lilly and Company | Pharmaceuticals | $1.04T | 41.2 | 0.5% | 12 |
| 2 | JNJ | Johnson & Johnson | Pharmaceuticals | $602B | 28.7 | 1.1% | 12 |
| 3 | ABBV | AbbVie Inc | Biotechnology | $449B | 118.9 | 2.8% | 12 |
| 4 | UNH | UnitedHealth Group Incorporated | Managed Health Care | $384B | 31.5 | 0.0% | 12 |
| 5 | MRK | Merck & Company Inc | Pharmaceuticals | $315B | 36.0 | 2.6% | 12 |
| 6 | NVS | Novartis AG ADR | Pharmaceuticals | $291B | 21.9 | 3.1% | 12 |
| 7 | AZN | AstraZeneca PLC | Pharmaceuticals | $263B | 25.6 | 1.9% | 12 |
| 8 | NVO | Novo Nordisk A/S | Pharmaceuticals | $228B | 12.1 | 3.6% | 12 |
| 9 | TMO | Thermo Fisher Scientific Inc | Life Sciences Tools & Services | $202B | 29.4 | 0.3% | 12 |
| 10 | AMGN | Amgen Inc | Biotechnology | $201B | 25.9 | 2.7% | 12 |
| 11 | ABT | Abbott Laboratories | Health Care Equipment | $172B | 25.0 | 0.0% | 12 |
| 12 | GILD | Gilead Sciences Inc | Biotechnology | $169B | 18.5 | 2.4% | 12 |
| 13 | DHR | Danaher Corporation | Health Care Equipment | $145B | 38.9 | 0.7% | 12 |
| 14 | PFE | Pfizer Inc | Pharmaceuticals | $143B | 18.9 | 6.9% | 12 |
| 15 | ISRG | Intuitive Surgical Inc | Health Care Equipment | $142B | 47.2 | — | 12 |
| 16 | CVS | CVS Health Corp | Health Care Services | $136B | 46.5 | 2.5% | 12 |
| 17 | SYK | Stryker Corporation | Health Care Equipment | $127B | 36.6 | 1.1% | 12 |
| 18 | BMY | Bristol-Myers Squibb Company | Pharmaceuticals | $124B | 16.9 | 4.3% | 12 |
| 19 | VRTX | Vertex Pharmaceuticals Inc | Biotechnology | $123B | 28.3 | — | 12 |
| 20 | MDT | Medtronic PLC | Health Care Equipment | $107B | 21.5 | 3.5% | 12 |
| 21 | SNY | Sanofi ADR | Pharmaceuticals | $106B | 19.6 | 0.0% | 12 |
| 22 | GSK | GlaxoSmithKline PLC ADR | Pharmaceuticals | $106B | 13.7 | 3.4% | 12 |
| 23 | MCK | McKesson Corporation | Health Care Distributors | $98.5B | 20.7 | 0.4% | 12 |
| 24 | HCA | HCA Healthcare, Inc. | Health Care Facilities | $85.6B | 13.1 | 0.8% | 12 |
| 25 | ELV | Elevance Health Inc | Managed Health Care | $80.9B | 16.5 | 1.8% | 12 |
| 26 | CI | Cigna Corp | Health Care Services | $75.1B | 12.6 | 2.0% | 12 |
| 27 | MDLN | Medline Inc. Class A Common Stock | Health Care Supplies | $73.2B | 36.1 | — | 4 |
| 28 | REGN | Regeneron Pharmaceuticals Inc | Biotechnology | $71.2B | 16.2 | 0.5% | 12 |
| 29 | BSX | Boston Scientific Corp | Health Care Equipment | $66.3B | 18.0 | — | 12 |
| 30 | COR | Cencora Inc. | Health Care Distributors | $59.9B | 22.7 | 0.8% | 12 |
| 31 | CAH | Cardinal Health Inc | Health Care Distributors | $53.9B | 35.2 | 0.9% | 12 |
| 32 | TAK | Takeda Pharmaceutical Co Ltd ADR | Pharmaceuticals | $53.4B | — | 3.8% | 12 |
| 33 | ARGX | argenx NV ADR | Biotechnology | $53.4B | 38.3 | — | 12 |
| 34 | EW | Edwards Lifesciences Corp | Health Care Equipment | $50.6B | 47.5 | — | 12 |
| 35 | GALDY | GALDERMA GROUP AG | Not classified by GICS | $49.1B | 80.6 | 0.2% | 5 |
| 36 | HUM | Humana Inc | Managed Health Care | $46.4B | 41.2 | 0.9% | 12 |
| 37 | IDXX | IDEXX Laboratories Inc | Health Care Equipment | $45.4B | 41.0 | — | 12 |
| 38 | HLN | Haleon plc | Biotechnology | $44.5B | 20.6 | 2.0% | 7 |
| 39 | BDX | Becton Dickinson and Company | Health Care Equipment | $44.1B | 27.0 | 2.7% | 12 |
| 40 | NTRA | Natera Inc | Biotechnology | $38.6B | — | — | 12 |
| 41 | A | Agilent Technologies Inc | Life Sciences Tools & Services | $38.4B | 27.0 | 0.8% | 12 |
| 42 | RVMD | Revolution Medicines Inc | Biotechnology | $38.1B | — | — | 9 |
| 43 | ALNY | Alnylam Pharmaceuticals Inc | Biotechnology | $37.8B | 69.9 | — | 12 |
| 44 | TEVA | Teva Pharma Industries Ltd ADR | Pharmaceuticals | $37.5B | 24.0 | — | 12 |
| 45 | WAT | Waters Corporation | Life Sciences Tools & Services | $37.1B | 48.1 | — | 12 |
| 46 | IQV | IQVIA Holdings Inc | Life Sciences Tools & Services | $35.1B | 25.7 | — | 12 |
| 47 | ALC | Alcon AG | Health Care Equipment | $34.4B | 41.1 | 0.5% | 11 |
| 48 | RPRX | Royalty Pharma Plc | Pharmaceuticals | $33.7B | 29.7 | 1.6% | 12 |
| 49 | ONC | BeiGene, Ltd. | Biotechnology | $32.9B | 70.4 | — | 12 |
| 50 | ZTS | Zoetis Inc | Pharmaceuticals | $32.2B | 12.2 | 2.7% | 12 |
| 51 | VEEV | Veeva Systems Inc Class A | Health Care Technology | $32.1B | 34.4 | — | 12 |
| 52 | CNC | Centene Corp | Managed Health Care | $31.5B | — | — | 12 |
| 53 | BIIB | Biogen Inc | Biotechnology | $30.8B | 22.4 | — | 12 |
| 54 | DXCM | DexCom Inc | Health Care Equipment | $30.1B | 33.5 | — | 12 |
| 55 | GEHC | GE HealthCare Technologies Inc. | Health Care Equipment | $29.9B | 15.1 | 0.2% | 7 |
| 56 | RMD | ResMed Inc | Health Care Equipment | $29.4B | 19.2 | 1.2% | 12 |
| 57 | ILMN | Illumina Inc | Life Sciences Tools & Services | $28.8B | 34.6 | — | 12 |
| 58 | MTD | Mettler-Toledo International Inc | Life Sciences Tools & Services | $27B | 31.3 | — | 12 |
| 59 | PHG | Koninklijke Philips NV ADR | Health Care Equipment | $26.5B | 23.9 | 3.8% | 12 |
| 60 | WST | West Pharmaceutical Services Inc | Health Care Supplies | $25.6B | 48.1 | 0.2% | 12 |
| 61 | MRNA | Moderna Inc | Biotechnology | $25.1B | — | — | 12 |
| 62 | ROIV | Roivant Sciences Ltd | Biotechnology | $24.4B | — | — | 8 |
| 63 | INCY | Incyte Corporation | Biotechnology | $23.3B | 16.3 | — | 12 |
| 64 | INSM | Insmed Inc | Biotechnology | $23.3B | — | — | 12 |
| 65 | DGX | Quest Diagnostics Incorporated | Health Care Services | $23.2B | 23.1 | 1.6% | 12 |
| 66 | BNTX | BioNTech SE | Biotechnology | $23.2B | — | — | 9 |
| 67 | LH | Laboratory Corporation of America Holdings | Health Care Services | $23.1B | 25.0 | 1.1% | 12 |
| 68 | UTHR | United Therapeutics Corporation | Biotechnology | $22.5B | 19.5 | — | 12 |
| 69 | STE | STERIS plc | Health Care Equipment | $20.6B | 26.3 | 1.2% | 12 |
| 70 | GH | Guardant Health Inc | Health Care Services | $20.6B | — | — | 10 |
| 71 | VTRS | Viatris Inc | Pharmaceuticals | $20.2B | — | 2.9% | 12 |
| 72 | ZBH | Zimmer Biomet Holdings Inc | Health Care Equipment | $18.1B | 23.4 | 1.1% | 12 |
| 73 | GMAB | Genmab AS | Biotechnology | $17.8B | 22.1 | — | 12 |
| 74 | NBIX | Neurocrine Biosciences Inc | Biotechnology | $17.2B | 26.5 | — | 12 |
| 75 | THC | Tenet Healthcare Corporation | Health Care Facilities | $17.2B | 10.4 | — | 12 |
| 76 | ASND | Ascendis Pharma AS | Biotechnology | $17B | 30.1 | — | 12 |
| 77 | BBIO | BridgeBio Pharma Inc | Biotechnology | $15.7B | — | — | 9 |
| 78 | MEDP | Medpace Holdings Inc | Life Sciences Tools & Services | $15.4B | 33.9 | — | 12 |
| 79 | JAZZ | Jazz Pharmaceuticals PLC | Pharmaceuticals | $15.2B | 2018.2 | — | 12 |
| 80 | DVA | DaVita HealthCare Partners Inc | Health Care Services | $15B | 22.3 | — | 12 |
| 81 | COO | The Cooper Companies, Inc | Health Care Supplies | $14.3B | 59.9 | — | 12 |
| 82 | SOLV | Solventum Corp. | Health Care Equipment | $14.1B | 9.6 | — | 6 |
| 83 | EXEL | Exelixis Inc | Biotechnology | $14B | 18.4 | — | 12 |
| 84 | BTSG | BrightSpring Health Services, Inc. Common Stock | Health Care Services | $13.4B | 88.5 | — | 8 |
| 85 | SNN | Smith & Nephew SNATS Inc | Health Care Equipment | $13.2B | 21.5 | 2.5% | 12 |
| 86 | ELAN | Elanco Animal Health | Pharmaceuticals | $13B | — | — | 11 |
| 87 | FMS | Fresenius Medical Care Corporation | Health Care Services | $12.9B | 13.0 | 3.6% | 12 |
| 88 | ICLR | ICON PLC | Life Sciences Tools & Services | $12.8B | 74.5 | — | 12 |
| 89 | ALGN | Align Technology Inc | Health Care Supplies | $12.8B | 30.5 | — | 12 |
| 90 | MDGL | Madrigal Pharmaceuticals Inc | Biotechnology | $12.6B | — | — | 12 |
| 91 | PEN | Penumbra Inc | Health Care Equipment | $12.6B | 73.0 | — | 12 |
| 92 | RVTY | Revvity Inc. | Life Sciences Tools & Services | $12.5B | 53.4 | 0.3% | 12 |
| 93 | AXSM | Axsome Therapeutics Inc | Pharmaceuticals | $12.2B | — | — | 12 |
| 94 | ABVX | Abivax SA American Depositary Shares | Biotechnology | $11.9B | — | — | 12 |
| 95 | MOH | Molina Healthcare Inc | Managed Health Care | $11.8B | 61.7 | — | 12 |
| 96 | BAX | Baxter International Inc | Health Care Equipment | $11.7B | — | 1.5% | 12 |
| 97 | BMRN | Biomarin Pharmaceutical Inc | Biotechnology | $11.6B | 42.3 | — | 12 |
| 98 | PODD | Insulet Corporation | Health Care Equipment | $11.4B | 38.4 | — | 12 |
| 99 | TECH | Bio-Techne Corp | Life Sciences Tools & Services | $11.2B | 103.0 | 0.4% | 12 |
| 100 | EHC | Encompass Health Corp | Health Care Facilities | $11.2B | 19.3 | 0.7% | 12 |
| 101 | CYTK | Cytokinetics Inc | Biotechnology | $11B | — | — | 12 |
| 102 | GMED | Globus Medical | Health Care Equipment | $11B | 18.3 | — | 12 |
| 103 | CRL | Charles River Laboratories | Life Sciences Tools & Services | $10.8B | — | — | 12 |
| 104 | SMMT | Summit Therapeutics PLC | Biotechnology | $10.7B | — | — | 12 |
| 105 | RDY | Dr. Reddy’s Laboratories Ltd ADR | Pharmaceuticals | $10.6B | 23.5 | 0.7% | 12 |
| 106 | KRYS | Krystal Biotech Inc | Biotechnology | $10.5B | 47.4 | — | 10 |
| 107 | APGE | Apogee Therapeutics, Inc. Common Stock | Biotechnology | $10.1B | — | — | 4 |
| 108 | ARWR | Arrowhead Pharmaceuticals Inc | Biotechnology | $10.1B | — | — | 12 |
| 109 | CORT | Corcept Therapeutics Incorporated | Pharmaceuticals | $9.86B | 262.5 | — | 12 |
| 110 | ENSG | The Ensign Group Inc | Health Care Facilities | $9.85B | 27.5 | 0.1% | 12 |
| 111 | KYMR | Kymera Therapeutics Inc | Biotechnology | $9.82B | — | — | 8 |
| 112 | NUVL | Nuvalent Inc | Biotechnology | $9.8B | — | — | 7 |
| 113 | IONS | Ionis Pharmaceuticals Inc | Biotechnology | $9.63B | — | — | 12 |
| 114 | HSIC | Henry Schein Inc | Health Care Distributors | $9.61B | 25.5 | — | 12 |
| 115 | TEM | Tempus AI, Inc. Class A Common Stock | Life Sciences Tools & Services | $9.42B | — | — | 7 |
| 116 | UHS | Universal Health Services Inc | Health Care Facilities | $9.15B | 6.3 | 0.5% | 12 |
| 117 | BRKR | Bruker Corporation | Life Sciences Tools & Services | $9.14B | — | 0.3% | 12 |
| 118 | PRAX | Praxis Precision Medicines Inc | Biotechnology | $9.06B | — | — | 8 |
| 119 | HALO | Halozyme Therapeutics Inc | Biotechnology | $9.04B | 26.7 | — | 12 |
| 120 | GKOS | Glaukos Corp | Health Care Equipment | $8.97B | — | — | 12 |
| 121 | CRNX | Crinetics Pharmaceuticals Inc | Biotechnology | $8.85B | — | — | 10 |
| 122 | TGTX | TG Therapeutics Inc | Biotechnology | $8.74B | 20.0 | — | 12 |
| 123 | ALKS | Alkermes Plc | Biotechnology | $8.66B | 57.7 | — | 12 |
| 124 | IBRX | Immunitybio Inc | Biotechnology | $8.61B | — | — | 12 |
| 125 | SYRE | Spyre Therapeutics Inc. | Biotechnology | $8.58B | — | — | 12 |
| 126 | QGEN | Qiagen NV | Life Sciences Tools & Services | $8.56B | 21.2 | 0.0% | 12 |
| 127 | PTGX | Protagonist Therapeutics Inc | Biotechnology | $8.45B | — | — | 12 |
| 128 | PCVX | Vaxcyte Inc | Biotechnology | $8.41B | — | — | 9 |
| 129 | IMVT | Immunovant Inc | Biotechnology | $8.15B | — | — | 10 |
| 130 | RGEN | Repligen Corporation | Life Sciences Tools & Services | $8.14B | 158.5 | — | 12 |
| 131 | BIO-B | Bio-Rad Laboratories Inc | Life Sciences Tools & Services | $7.99B | 49.8 | — | 12 |
| 132 | HIMS | Hims Hers Health Inc | Health Care Services | $7.96B | — | — | 8 |
| 133 | BIO | Bio-Rad Laboratories Inc | Life Sciences Tools & Services | $7.92B | 49.3 | — | 12 |
| 134 | HQY | HealthEquity Inc | Managed Health Care | $7.89B | 35.4 | — | 12 |
| 135 | MIRM | Mirum Pharmaceuticals Inc | Biotechnology | $7.45B | — | — | 8 |
| 136 | RYTM | Rhythm Pharmaceuticals Inc | Biotechnology | $7.44B | — | — | 12 |
| 137 | AVTR | Avantor Inc | Life Sciences Tools & Services | $7.18B | — | — | 11 |
| 138 | PTCT | PTC Therapeutics Inc | Biotechnology | $6.99B | — | — | 12 |
| 139 | LQDA | Liquidia Technologies Inc | Pharmaceuticals | $6.93B | 458.4 | — | 10 |
| 140 | LNTH | Lantheus Holdings Inc | Health Care Supplies | $6.88B | 25.2 | — | 12 |
| 141 | PACS | PACS Group, Inc. | Health Care Facilities | $6.84B | 28.2 | — | 5 |
| 142 | SRRK | Scholar Rock Holding Corp | Biotechnology | $6.8B | — | — | 10 |
| 143 | XENE | Xenon Pharmaceuticals Inc | Biotechnology | $6.66B | — | — | 12 |
| 144 | COGT | Cogent Biosciences Inc | Biotechnology | $6.64B | — | — | 11 |
| 145 | CGON | CG Oncology, Inc. Common stock | Biotechnology | $6.64B | — | — | 5 |
| 146 | CHE | Chemed Corp | Health Care Services | $6.49B | 26.7 | 0.5% | 12 |
| 147 | LGND | Ligand Pharmaceuticals Incorporated | Biotechnology | $6.34B | 41.2 | — | 12 |
| 148 | DFTX | Definium Therapeutics, Inc. | Pharmaceuticals | $6.25B | — | — | 11 |
| 149 | TFX | Teleflex Incorporated | Health Care Equipment | $6.01B | 2714.6 | 1.0% | 12 |
| 150 | BLTE | Belite Bio Inc ADR | Biotechnology | $5.99B | — | — | 6 |
| 151 | BLCO | Bausch + Lomb Corp | Health Care Supplies | $5.79B | — | — | 8 |
| 152 | ERAS | Erasca Inc | Biotechnology | $5.76B | — | — | 7 |
| 153 | TWST | Twist Bioscience Corp | Biotechnology | $5.64B | — | — | 10 |
| 154 | CRSP | Crispr Therapeutics AG | Biotechnology | $5.55B | — | — | 12 |
| 155 | CELC | Celcuity LLC | Biotechnology | $5.54B | — | — | 11 |
| 156 | AMRX | Amneal Pharmaceuticals, Inc. Class A Common Stock | Pharmaceuticals | $5.43B | 46.0 | — | 12 |
| 157 | TXG | 10X Genomics Inc | Life Sciences Tools & Services | $5.42B | — | — | 9 |
| 158 | STVN | Stevanato Group SpA | Health Care Equipment | $5.35B | 33.8 | 0.0% | 7 |
| 159 | DNTH | Dianthus Therapeutics Inc. | Biotechnology | $5.32B | — | — | 10 |
| 160 | TVTX | Travere Therapeutics Inc | Biotechnology | $5.26B | — | — | 12 |
| 161 | SHC | Sotera Health Co | Life Sciences Tools & Services | $5.25B | 44.9 | — | 10 |
| 162 | APLS | Apellis Pharmaceuticals Inc | Biotechnology | $5.25B | 38.3 | — | 12 |
| 163 | LEGN | Legend Biotech Corp | Biotechnology | $5.24B | — | — | 9 |
| 164 | ORKA | Oruka Therapeutics, Inc. | Biotechnology | $5.23B | — | — | 12 |
| 165 | RDNT | RadNet Inc | Health Care Services | $5.16B | — | — | 12 |
| 166 | TNGX | Tango Therapeutics Inc | Biotechnology | $5.06B | — | — | 7 |
| 167 | GRFS | Grifols SA ADR | Biotechnology | $4.95B | 10.5 | 3.9% | 12 |
| 168 | EWTX | Edgewise Therapeutics Inc | Biotechnology | $4.89B | — | — | 7 |
| 169 | KNSA | Kiniksa Pharmaceuticals Ltd | Biotechnology | $4.88B | 69.7 | — | 10 |
| 170 | CAI | Caris Life Sciences, Inc. Common Stock | Life Sciences Tools & Services | $4.8B | — | — | 12 |
| 171 | INDV | Indivior PLC Ordinary Shares | Biotechnology | $4.79B | 21.2 | — | 10 |
| 172 | VCYT | Veracyte Inc | Biotechnology | $4.55B | 52.8 | — | 12 |
| 173 | LIVN | LivaNova PLC | Health Care Equipment | $4.54B | 42.1 | — | 12 |
| 174 | VKTX | Viking Therapeutics Inc | Biotechnology | $4.51B | — | — | 12 |
| 175 | ACAD | ACADIA Pharmaceuticals Inc | Biotechnology | $4.49B | 11.9 | — | 12 |
| 176 | WAY | Waystar Holding Corp. Common Stock | Health Care Technology | $4.45B | 34.1 | — | 5 |
| 177 | MMSI | Merit Medical Systems Inc | Health Care Supplies | $4.38B | 31.7 | — | 12 |
| 178 | RLAY | Relay Therapeutics Inc | Biotechnology | $4.36B | — | — | 8 |
| 179 | MMED | MiniMed Group, Inc. Common Stock | Not classified by GICS | $4.29B | — | — | 4 |
| 180 | NVST | Envista Holdings Corp | Health Care Equipment | $4.22B | 63.2 | — | 11 |
| 181 | NAMS | NewAmsterdam Pharma Company N.V. Ordinary Shares | Biotechnology | $4.2B | — | — | 6 |
| 182 | PINC | Premier Inc | Health Care Services | $4.15B | 294.3 | 0.0% | 12 |
| 183 | ALHC | Alignment Healthcare LLC | Health Care Services | $4.1B | 198.3 | — | 7 |
| 184 | LFST | Lifestance Health Group Inc | Health Care Equipment | $4.09B | 178.4 | — | 7 |
| 185 | DNLI | Denali Therapeutics Inc | Biotechnology | $4.08B | — | — | 11 |
| 186 | CON | Concentra Group Holdings Parent, Inc. | Health Care Services | $4.04B | 22.5 | 0.8% | 5 |
| 187 | DOCS | Doximity Inc | Health Care Technology | $3.98B | 22.2 | — | 8 |
| 188 | GPCR | Structure Therapeutics Inc. American Depositary Shares | Biotechnology | $3.92B | — | — | 6 |
| 189 | DYN | Dyne Therapeutics Inc | Biotechnology | $3.87B | — | — | 12 |
| 190 | ICUI | ICU Medical Inc | Health Care Supplies | $3.86B | 83.5 | — | 12 |
| 191 | CPRX | Catalyst Pharmaceuticals Inc | Biotechnology | $3.85B | 18.2 | — | 12 |
| 192 | IRTC | iRhythm Technologies Inc | Health Care Equipment | $3.82B | — | — | 12 |
| 193 | TLX | Telix Pharmaceuticals Limited | Pharmaceuticals | $3.77B | — | — | 12 |
| 194 | ELVN | Enliven Therapeutics Inc. | Pharmaceuticals | $3.65B | — | — | 9 |
| 195 | RCUS | Arcus Biosciences Inc | Biotechnology | $3.64B | — | — | 10 |
| 196 | ALMS | Alumis Inc | Biotechnology | $3.61B | — | — | 4 |
| 197 | IDYA | Ideaya Biosciences Inc | Biotechnology | $3.56B | — | — | 9 |
| 198 | OGN | Organon & Co | Pharmaceuticals | $3.55B | 14.5 | 0.6% | 9 |
| 199 | NHC | National HealthCare Corporation | Health Care Facilities | $3.51B | 28.6 | 1.2% | 12 |
| 200 | ARQT | Arcutis Biotherapeutics Inc | Biotechnology | $3.47B | — | — | 9 |
| 201 | PRVA | Privia Health Group Inc | Health Care Services | $3.46B | 161.7 | — | 8 |
| 202 | HAE | Haemonetics Corporation | Health Care Supplies | $3.46B | 37.2 | — | 12 |
| 203 | BKD | Brookdale Senior Living Inc | Health Care Facilities | $3.44B | — | — | 12 |
| 204 | OPCH | Option Care Health Inc | Health Care Services | $3.39B | 16.9 | — | 12 |
| 205 | ADPT | Adaptive Biotechnologies Corp | Life Sciences Tools & Services | $3.37B | — | — | 9 |
| 206 | BEAM | Beam Therapeutics Inc | Biotechnology | $3.36B | — | — | 9 |
| 207 | RARE | Ultragenyx | Biotechnology | $3.33B | — | — | 12 |
| 208 | ITGR | Integer Holdings Corp | Health Care Equipment | $3.18B | 23.2 | — | 12 |
| 209 | CRVL | CorVel Corp | Health Care Services | $3.18B | 29.1 | — | 12 |
| 210 | GRAL | GRAIL, LLC | Biotechnology | $3.09B | — | — | 8 |
| 211 | CLDX | Celldex Therapeutics Inc | Biotechnology | $3.07B | — | — | 12 |
| 212 | VERA | Vera Therapeutics Inc | Biotechnology | $3.01B | — | — | 7 |
| 213 | QURE | Uniqure NV | Biotechnology | $2.93B | — | — | 12 |
| 214 | MBX | MBX Biosciences, Inc. Common Stock | Biotechnology | $2.91B | — | — | 4 |
| 215 | IRON | Disc Medicine Inc. | Biotechnology | $2.9B | — | — | 6 |
| 216 | ACHC | Acadia Healthcare Company Inc | Health Care Facilities | $2.88B | — | — | 12 |
| 217 | SUPN | Supernus Pharmaceuticals Inc | Pharmaceuticals | $2.81B | — | — | 12 |
| 218 | BCRX | BioCryst Pharmaceuticals Inc | Biotechnology | $2.66B | — | — | 12 |
| 219 | IMNM | Immunome Inc | Biotechnology | $2.64B | — | — | 8 |
| 220 | ESTA | Establishment Labs Holdings Inc | Health Care Supplies | $2.59B | — | — | 11 |
| 221 | KOD | Kodiak Sciences Inc | Biotechnology | $2.59B | — | — | 10 |
| 222 | TARS | Tarsus Pharmaceuticals Inc | Pharmaceuticals | $2.54B | — | — | 8 |
| 223 | TRVI | Trevi Therapeutics Inc | Pharmaceuticals | $2.53B | — | — | 10 |
| 224 | SLS | Sellas Life Sciences Group Inc | Biotechnology | $2.51B | — | — | 12 |
| 225 | RGC | Regencell Bioscience Holdings Ltd | Biotechnology | $2.5B | — | — | 12 |
| 226 | TMDX | TransMedics Group Inc | Health Care Equipment | $2.46B | 16.3 | — | 11 |
| 227 | XRAY | Dentsply Sirona Inc | Health Care Supplies | $2.46B | — | 4.0% | 12 |
| 228 | AGIO | Agios Pharm | Biotechnology | $2.45B | — | — | 12 |
| 229 | PHVS | Pharvaris BV | Biotechnology | $2.45B | — | — | 8 |
| 230 | MLYS | Mineralys Therapeutics, Inc. Common Stock | Biotechnology | $2.45B | — | — | 6 |
| 231 | PGNY | Progyny Inc | Health Care Services | $2.4B | 39.8 | — | 9 |
| 232 | VCEL | Vericel Corp Ord | Biotechnology | $2.4B | 109.3 | — | 12 |
| 233 | NRIX | Nurix Therapeutics Inc | Biotechnology | $2.39B | — | — | 8 |
| 234 | NKTR | Nektar Therapeutics | Pharmaceuticals | $2.38B | — | — | 12 |
| 235 | LMAT | LeMaitre Vascular Inc | Health Care Equipment | $2.35B | 37.8 | 0.8% | 12 |
| 236 | BHVN | Biohaven Ltd. | Biotechnology | $2.34B | — | — | 8 |
| 237 | CLOV | Clover Health Investments Corp | Health Care Services | $2.34B | — | — | 8 |
| 238 | ASTH | Astrana Health Inc | Health Care Services | $2.32B | 76.8 | — | 12 |
| 239 | PBH | Prestige Brand Holdings Inc | Pharmaceuticals | $2.32B | 12.5 | — | 12 |
| 240 | ZLAB | Zai Lab Ltd | Biotechnology | $2.31B | — | — | 11 |
| 241 | MRVI | Maravai Lifesciences Holdings Inc | Life Sciences Tools & Services | $2.25B | — | — | 8 |
| 242 | OCUL | Ocular Therapeutix Inc | Pharmaceuticals | $2.23B | — | — | 12 |
| 243 | VRDN | Viridian Therapeutics Inc | Biotechnology | $2.18B | — | — | 12 |
| 244 | AXGN | Axogen Inc | Health Care Equipment | $2.16B | — | — | 12 |
| 245 | MD | Mednax Inc | Health Care Services | $2.16B | 12.8 | — | 12 |
| 246 | SGRY | Surgery Partners Inc | Health Care Facilities | $2.14B | — | — | 12 |
| 247 | HRMY | Harmony Biosciences Holdings | Pharmaceuticals | $2.13B | 14.9 | — | 8 |
| 248 | AVAH | Aveanna Healthcare Holdings Inc | Health Care Equipment | $2.11B | 8.0 | — | 8 |
| 249 | ADMA | ADMA Biologics Inc | Biotechnology | $2.1B | 13.4 | — | 12 |
| 250 | NEOG | Neogen Corporation | Health Care Supplies | $2.09B | — | — | 12 |
| 251 | SNDX | Syndax Pharmaceuticals Inc | Biotechnology | $2.09B | — | — | 12 |
| 252 | BFLY | Butterfly Network Inc | Health Care Equipment | $2.09B | — | — | 8 |
| 253 | PVLA | Palvella Therapeutics, Inc | Biotechnology | $2.08B | — | — | 12 |
| 254 | WGS | GeneDx Holdings Corp. | Health Care Equipment | $2.06B | — | — | 7 |
| 255 | SEM | Select Medical Holdings | Health Care Facilities | $2.05B | 15.4 | 1.5% | 12 |
| 256 | OMCL | Omnicell Inc | Health Care Technology | $2.04B | 102.1 | — | 12 |
| 257 | NBTX | Nanobiotix | Biotechnology | $2.03B | — | — | 12 |
| 258 | AUPH | Aurinia Pharmaceuticals Inc | Biotechnology | $2.03B | 7.3 | — | 12 |
| 259 | NUVB | Nuvation Bio Inc | Biotechnology | $2.02B | — | — | 8 |
| 260 | ADUS | Addus HomeCare Corporation | Health Care Services | $2.02B | 20.0 | — | 12 |
| 261 | SRPT | Sarepta Therapeutics Inc | Biotechnology | $2B | 54.1 | — | 12 |
| 262 | RAPP | Rapport Therapeutics, Inc. Common Stock | Pharmaceuticals | $2B | — | — | 4 |
| 263 | MESO | Mesoblast Ltd | Biotechnology | $2B | — | — | 12 |
| 264 | PIII | P3 Health Partners Inc | Health Care Equipment | $1.99B | — | — | 8 |
| 265 | SION | Sionna Therapeutics, Inc. Common Stock | Biotechnology | $1.99B | — | — | 4 |
| 266 | NTLA | Intellia Therapeutics Inc | Biotechnology | $1.99B | — | — | 12 |
| 267 | AMLX | Amylyx Pharmaceuticals Inc | Pharmaceuticals | $1.98B | — | — | 7 |
| 268 | ANAB | AnaptysBio Inc | Biotechnology | $1.97B | — | — | 12 |
| 269 | STOK | Stoke Therapeutics Inc | Biotechnology | $1.95B | — | — | 9 |
| 270 | LKFT | Lakefront Biotherapeutics NV | Not classified by GICS | $1.95B | 3.5 | — | 4 |
| 271 | TYRA | Tyra Biosciences Inc | Biotechnology | $1.95B | — | — | 7 |
| 272 | GLUE | Monte Rosa Therapeutics Inc | Biotechnology | $1.95B | — | — | 7 |
| 273 | AGL | agilon health Inc | Health Care Services | $1.92B | — | — | 7 |
| 274 | SNDA | Sonida Senior Living Inc | Health Care Equipment | $1.92B | — | — | 12 |
| 275 | ZYME | Zymeworks Inc. Common Stock | Biotechnology | $1.9B | — | — | 12 |
| 276 | HCM | HUTCHMED DRC | Pharmaceuticals | $1.9B | 4.2 | — | 12 |
| 277 | ATAI | ATAI Life Sciences BV | Biotechnology | $1.9B | — | — | 7 |
| 278 | BCAX | Bicara Therapeutics Inc. Common Stock | Biotechnology | $1.9B | — | — | 4 |
| 279 | PGEN | Precigen Inc | Biotechnology | $1.9B | — | — | 12 |
| 280 | RXRX | Recursion Pharmaceuticals Inc | Biotechnology | $1.89B | — | — | 7 |
| 281 | IOVA | Iovance Biotherapeutics Inc | Biotechnology | $1.89B | — | — | 12 |
| 282 | NVCR | Novocure Ltd | Health Care Equipment | $1.89B | — | — | 12 |
| 283 | URGN | UroGen Pharma Ltd | Biotechnology | $1.88B | — | — | 12 |
| 284 | ANIP | ANI Pharmaceuticals Inc | Pharmaceuticals | $1.87B | 21.0 | — | 12 |
| 285 | CMPS | Compass Pathways Plc | Health Care Services | $1.84B | — | — | 8 |
| 286 | NEO | NeoGenomics Inc | Health Care Services | $1.84B | — | — | 12 |
| 287 | UFPT | UFP Technologies Inc | Health Care Supplies | $1.83B | 27.0 | — | 12 |
| 288 | ABCL | Abcellera Biologics Inc | Biotechnology | $1.82B | — | — | 8 |
| 289 | TSHA | Taysha Gene Therapies Inc | Biotechnology | $1.82B | — | — | 7 |
| 290 | PLSE | Pulse Biosciences Inc | Health Care Equipment | $1.82B | — | — | 12 |
| 291 | GHRS | GH Research PLC | Biotechnology | $1.82B | — | — | 7 |
| 292 | ZBIO | Zenas BioPharma, Inc. Common Stock | Biotechnology | $1.81B | — | — | 4 |
| 293 | MPLT | MapLight Therapeutics, Inc. Common Stock | Biotechnology | $1.8B | — | — | 4 |
| 294 | ABSI | Absci Corp | Biotechnology | $1.8B | — | — | 7 |
| 295 | BHC | Bausch Health Companies Inc | Pharmaceuticals | $1.79B | — | — | 12 |
| 296 | AAPG | Ascentage Pharma Group International | Biotechnology | $1.78B | — | — | 10 |
| 297 | DMRA | Damora Therapeutics, Inc. | Not classified by GICS | $1.76B | — | — | 8 |
| 298 | ATRC | AtriCure Inc | Health Care Equipment | $1.74B | — | — | 12 |
| 299 | MAZE | Maze Therapeutics, Inc. Common Stock | Pharmaceuticals | $1.69B | — | — | 4 |
| 300 | VIR | Vir Biotechnology Inc | Biotechnology | $1.68B | — | — | 9 |
| 301 | FIGS | Figs Inc | Health Care Supplies | $1.68B | 45.6 | — | 7 |
| 302 | TDOC | Teladoc Inc | Health Care Technology | $1.68B | — | — | 12 |
| 303 | FTRE | Fortrea Holdings Inc. | Life Sciences Tools & Services | $1.66B | — | — | 6 |
| 304 | MLTX | MoonLake Immunotherapeutics | Biotechnology | $1.65B | — | — | 6 |
| 305 | INVA | Innoviva Inc | Pharmaceuticals | $1.64B | 3.6 | — | 12 |
| 306 | IMCR | Immunocore Holdings Ltd | Biotechnology | $1.63B | — | — | 12 |
| 307 | SEPN | Septerna, Inc. Common Stock | Pharmaceuticals | $1.62B | — | — | 4 |
| 308 | HROW | Harrow Health Inc | Pharmaceuticals | $1.58B | — | — | 12 |
| 309 | AVBP | ArriVent BioPharma, Inc. Common Stock | Biotechnology | $1.57B | — | — | 5 |
| 310 | INNV | InnovAge Holding Corp | Health Care Services | $1.56B | — | — | 11 |
| 311 | AKTS | Aktis Oncology, Inc. Common stock | Not classified by GICS | $1.54B | — | — | 11 |
| 312 | NVAX | Novavax Inc | Biotechnology | $1.53B | — | — | 12 |
| 313 | KMTS | Kestra Medical Technologies, Ltd. Common Stock | Health Care Equipment | $1.52B | — | — | 5 |
| 314 | INSP | Inspire Medical Systems Inc | Health Care Technology | $1.49B | 11.8 | — | 11 |
| 315 | ENOV | Enovis Corp | Health Care Equipment | $1.48B | — | — | 12 |
| 316 | PSNL | Personalis Inc | Life Sciences Tools & Services | $1.47B | — | — | 9 |
| 317 | ATEC | Alphatec Holdings Inc | Health Care Equipment | $1.47B | — | — | 12 |
| 318 | CDNA | CareDx Inc | Biotechnology | $1.47B | — | — | 12 |
| 319 | IART | Integra LifeSciences Holdings | Health Care Equipment | $1.46B | — | — | 12 |
| 320 | ARDT | Ardent Health Partners, Inc. | Health Care Facilities | $1.45B | 10.7 | — | 9 |
| 321 | XERS | Xeris Pharmaceuticals Inc | Pharmaceuticals | $1.44B | 119.1 | — | 10 |
| 322 | PRGO | Perrigo Company PLC | Pharmaceuticals | $1.41B | — | 11.1% | 12 |
| 323 | PNTG | Pennant Group Inc | Health Care Facilities | $1.41B | 47.1 | — | 10 |
| 324 | AHCO | Adapthealth Corp | Health Care Distributors | $1.39B | — | — | 10 |
| 325 | OMDA | Omada Health, Inc. Common Stock | Health Care Technology | $1.38B | — | — | 4 |
| 326 | STAA | STAAR Surgical Company | Health Care Supplies | $1.38B | — | — | 12 |
| 327 | BLFS | BioLife Solutions Inc | Health Care Supplies | $1.38B | — | — | 12 |
| 328 | INBX | Inhibrx Biosciences, Inc. | Biotechnology | $1.36B | — | — | 10 |
| 329 | IMTX | Immatics NV | Biotechnology | $1.32B | — | — | 8 |
| 330 | CRVS | Corvus Pharmaceuticals Inc | Biotechnology | $1.32B | — | — | 12 |
| 331 | ARDX | Ardelyx Inc | Biotechnology | $1.3B | — | — | 12 |
| 332 | AHG | Akso Health Group ADR | Health Care Equipment | $1.3B | — | — | 11 |
| 333 | PAHC | Phibro Animal Health Corporation | Pharmaceuticals | $1.3B | 13.8 | 1.5% | 12 |
| 334 | JBIO | Jade Biosciences, Inc. | Biotechnology | $1.28B | — | — | 6 |
| 335 | NUTX | Nutex Health Inc | Health Care Equipment | $1.27B | 13.5 | — | 12 |
| 336 | MNKD | MannKind Corp | Biotechnology | $1.26B | — | — | 12 |
| 337 | AMN | AMN Healthcare Services Inc | Health Care Services | $1.26B | — | — | 12 |
| 338 | QDEL | Quidel Corporation | Health Care Supplies | $1.25B | — | — | 12 |
| 339 | CAPR | Capricor Therapeutics Inc | Biotechnology | $1.25B | — | — | 12 |
| 340 | IRMD | Iradimed Co | Health Care Equipment | $1.24B | 53.1 | 0.8% | 12 |
| 341 | MGTX | MeiraGTx Holdings PLC | Biotechnology | $1.24B | — | — | 10 |
| 342 | SVRA | Savara Inc | Biotechnology | $1.24B | — | — | 12 |
| 343 | EYPT | EyePoint, Inc | Pharmaceuticals | $1.23B | — | — | 12 |
| 344 | SDGR | Schrodinger Inc | Health Care Technology | $1.23B | — | — | 9 |
| 345 | WVE | Wave Life Sciences Ltd | Pharmaceuticals | $1.2B | — | — | 12 |
| 346 | PRCT | Procept Biorobotics Corp | Health Care Equipment | $1.19B | — | — | 7 |
| 347 | XNCR | Xencor Inc | Biotechnology | $1.18B | — | — | 12 |
| 348 | AORT | Artivion Inc | Health Care Equipment | $1.17B | 96.4 | — | 12 |
| 349 | AZTA | Azenta Inc | Life Sciences Tools & Services | $1.17B | — | — | 12 |
| 350 | AVNS | Avanos Medical Inc | Health Care Supplies | $1.17B | — | — | 12 |
| 351 | CNMD | CONMED Corporation | Health Care Equipment | $1.16B | 21.7 | 1.1% | 12 |
| 352 | DRTS | Alpha Tau Medical Ltd | Biotechnology | $1.15B | — | — | 7 |
| 353 | COLL | Collegium Pharmaceutical Inc | Pharmaceuticals | $1.14B | 17.1 | — | 12 |
| 354 | ORIC | Oric Pharmaceuticals Inc | Biotechnology | $1.12B | — | — | 9 |
| 355 | ALVO | Alvotech | Biotechnology | $1.12B | — | — | 7 |
| 356 | CGEM | Cullinan Oncology LLC | Biotechnology | $1.11B | — | — | 12 |
| 357 | USPH | U.S. Physical Therapy, Inc. | Health Care Facilities | $1.1B | 145.1 | 2.5% | 12 |
| 358 | BIOA | BioAge Labs, Inc | Pharmaceuticals | $1.08B | — | — | 9 |
| 359 | SANA | Sana Biotechnology Inc | Biotechnology | $1.07B | — | — | 8 |
| 360 | TNDM | Tandem Diabetes Care Inc | Health Care Equipment | $1.06B | — | — | 12 |
| 361 | CERT | Certara Inc | Health Care Technology | $1.05B | — | — | 8 |
| 362 | OLMA | Olema Pharmaceuticals Inc | Biotechnology | $1.04B | — | — | 8 |
| 363 | VOR | Vor Biopharma Inc | Biotechnology | $1.04B | — | — | 8 |
| 364 | CRON | Cronos Group Inc | Pharmaceuticals | $1.03B | — | — | 12 |
| 365 | SLDB | Solid Biosciences LLC | Biotechnology | $1.03B | — | — | 11 |
| 366 | OPK | Opko Health Inc | Biotechnology | $1.02B | — | — | 12 |
| 367 | KURA | Kura Oncology Inc | Biotechnology | $1.02B | — | — | 12 |
| 368 | IVA | Inventiva Sa | Biotechnology | $1.02B | — | — | 12 |
| 369 | AVTX | Avalo Therapeutics Inc | Biotechnology | $1.01B | — | — | 12 |
| 370 | BTX | BlackRock Technology and Private Equity Term Trust | Biotechnology | $1.01B | 23.4 | 0.0% | 12 |
| 371 | PHAT | Phathom Pharmaceuticals Inc | Pharmaceuticals | $1.01B | — | — | 8 |
| 372 | ETON | Eton Pharmaceuticals Inc | Pharmaceuticals | $1B | — | — | 9 |
| 373 | PCRX | Pacira BioSciences, Inc. | Pharmaceuticals | $1B | 196.0 | — | 12 |
| 374 | JANX | Janux Therapeutics Inc | Biotechnology | $1B | — | — | 7 |
| 375 | GDRX | Goodrx Holdings Inc | Health Care Technology | $999M | 49.2 | — | 10 |
| 376 | GRCL | Gracell Biotechnologies Inc. | Biotechnology | $990M | — | — | 6 |
| 377 | EVO | Evotec SE ADR | Biotechnology | $989M | — | — | 12 |
| 378 | LXRX | Lexicon Pharmaceuticals Inc | Biotechnology | $986M | — | — | 12 |
| 379 | PHAR | Pharming Group NV | Biotechnology | $979M | 72.9 | — | 12 |
| 380 | DBVT | DBV Technologies | Biotechnology | $976M | — | — | 12 |
| 381 | BMEZ | BlackRock Health Sciences Trust II | Health Care Services | $968M | 6.1 | 0.0% | 6 |
| 382 | GERN | Geron Corporation | Biotechnology | $962M | — | — | 12 |
| 383 | AVR | Anteris Technologies Global Corp. Common Stock | Health Care Equipment | $951M | — | — | 6 |
| 384 | ANNX | Annexon Inc | Biotechnology | $950M | — | — | 9 |
| 385 | DSGN | Design Therapeutics Inc | Biotechnology | $949M | — | — | 7 |
| 386 | ABUS | Arbutus Biopharma Corp | Biotechnology | $948M | 5.8 | — | 12 |
| 387 | LBRX | LB Pharmaceuticals Inc Common Stock | Pharmaceuticals | $945M | — | — | 4 |
| 388 | ANRO | Alto Neuroscience, Inc. | Pharmaceuticals | $941M | — | — | 5 |
| 389 | FTH | Faeth Therapeutics, Inc. | Not classified by GICS | $932M | — | — | 8 |
| 390 | REPL | Replimune Group Inc | Biotechnology | $923M | — | — | 10 |
| 391 | FBRX | Forte Biosciences Inc | Biotechnology | $899M | — | — | 11 |
| 392 | INMD | InMode Ltd | Health Care Equipment | $878M | 11.3 | — | 10 |
| 393 | TBPH | Theravance Biopharma Inc | Pharmaceuticals | $877M | 7.6 | — | 12 |
| 394 | TALK | Talkspace Inc | Health Care Equipment | $876M | — | — | 8 |
| 395 | NGNE | Neurogene Inc | Biotechnology | $855M | — | — | 12 |
| 396 | AMPH | Amphastar P | Pharmaceuticals | $825M | 11.3 | — | 12 |
| 397 | OCS | Oculis Holding AG Ordinary shares | Biotechnology | $823M | — | — | 6 |
| 398 | HSTM | HealthStream Inc | Health Care Technology | $820M | 41.9 | 0.5% | 12 |
| 399 | ESPR | Esperion Therapeutics Inc | Biotechnology | $819M | — | — | 12 |
| 400 | CTMX | CytomX Therapeutics Inc | Biotechnology | $819M | — | — | 12 |
| 401 | ODTX | Odyssey Therapeutics, Inc. Common Stock | Not classified by GICS | $817M | — | — | 4 |
| 402 | CYRX | Cryoport Inc | Health Care Equipment | $815M | — | — | 12 |
| 403 | BVS | Bioventus Inc | Health Care Equipment | $805M | 29.0 | — | 12 |
| 404 | ZVRA | Zevra Therapeutics Inc. | Biotechnology | $793M | 7.0 | — | 12 |
| 405 | IMMX | Immix Biopharma Inc | Biotechnology | $791M | — | — | 7 |
| 406 | SPRY | ARS Pharmaceuticals, Inc | Biotechnology | $788M | — | — | 8 |
| 407 | RIGL | Rigel Pharmaceuticals Inc | Biotechnology | $787M | 2.2 | — | 12 |
| 408 | XOMA | XOMA Royalty Corporation | Biotechnology | $782M | 28.2 | — | 12 |
| 409 | ACRS | Aclaris Therapeutics Inc | Pharmaceuticals | $779M | — | — | 12 |
| 410 | SIBN | Si-Bone Inc | Health Care Supplies | $779M | — | — | 12 |
| 411 | CLYM | Climb Bio Inc | Biotechnology | $771M | — | — | 7 |
| 412 | DRUG | Bright Minds Biosciences Inc | Biotechnology | $764M | — | — | 7 |
| 413 | BBNX | Beta Bionics, Inc. Common Stock | Health Care Equipment | $759M | — | — | 4 |
| 414 | SSII | SS Innovations International Inc. Common Stock | Health Care Equipment | $756M | — | — | 11 |
| 415 | OMER | Omeros Corporation | Pharmaceuticals | $740M | 9.0 | — | 12 |
| 416 | CBLL | CeriBell, Inc | Health Care Equipment | $738M | — | — | 4 |
| 417 | IRWD | Ironwood Pharmaceuticals Inc | Biotechnology | $736M | 7.2 | — | 12 |
| 418 | GYRE | Gyre Therapeutics Inc. | Biotechnology | $727M | — | — | 12 |
| 419 | RGNX | Regenxbio Inc | Biotechnology | $721M | — | — | 12 |
| 420 | CSTL | Castle Biosciences Inc | Biotechnology | $719M | — | — | 9 |
| 421 | MNPR | Monopar Therapeutics Inc | Biotechnology | $714M | — | — | 11 |
| 422 | AURA | Aura Biosciences Inc | Biotechnology | $708M | — | — | 7 |
| 423 | CADL | Candel Therapeutics Inc | Biotechnology | $695M | — | — | 7 |
| 424 | ALLO | Allogene Therapeutics Inc | Biotechnology | $690M | — | — | 9 |
| 425 | PRME | Prime Medicine, Inc. Common Stock | Biotechnology | $683M | — | — | 7 |
| 426 | RLMD | Relmada Therapeutics Inc | Pharmaceuticals | $673M | — | — | 12 |
| 427 | TCMD | Tactile Systems Technology Inc | Health Care Equipment | $673M | 34.3 | — | 12 |
| 428 | BBOT | BridgeBio Oncology Therapeutics, Inc. | Biotechnology | $666M | — | — | 5 |
| 429 | PHR | Phreesia Inc | Health Care Technology | $662M | 67.0 | — | 9 |
| 430 | CRMD | CorMedix Inc | Pharmaceuticals | $659M | 3.9 | — | 12 |
| 431 | TECX | Tectonic Therapeutic, Inc. | Biotechnology | $654M | — | — | 10 |
| 432 | AGMB | AgomAb Therapeutics NV American Depositary Shares | Not classified by GICS | $644M | — | — | 4 |
| 433 | FDMT | 4D Molecular Therapeutics Inc | Biotechnology | $644M | — | — | 9 |
| 434 | SVA | Sinovac Biotech Ltd | Biotechnology | $642M | 6.7 | — | 12 |
| 435 | ANL | Adlai Nortye Ltd. American Depositary Shares | Biotechnology | $642M | — | — | 7 |
| 436 | STTK | Shattuck Labs Inc | Biotechnology | $634M | — | — | 8 |
| 437 | EVH | Evolent Health Inc | Health Care Technology | $633M | — | — | 12 |
| 438 | ACHV | Achieve Life Sciences Inc | Biotechnology | $627M | — | — | 12 |
| 439 | CERS | Cerus Corporation | Health Care Supplies | $625M | — | — | 12 |
| 440 | MDXG | MiMedx Group Inc | Biotechnology | $612M | 20.6 | — | 12 |
| 441 | BWAY | Brainsway Ltd | Health Care Equipment | $604M | 68.5 | — | 12 |
| 442 | CTKB | Cytek Biosciences Inc | Health Care Equipment | $597M | — | — | 7 |
| 443 | DNA | Ginkgo Bioworks Holdings | Biotechnology | $594M | — | — | 7 |
| 444 | ALT | Altimmune Inc | Biotechnology | $593M | — | — | 12 |
| 445 | TOI | Oncology Institute Inc | Health Care Equipment | $589M | — | — | 8 |
| 446 | FLGT | Fulgent Genetics Inc | Health Care Services | $584M | — | — | 12 |
| 447 | NPCE | Neuropace Inc | Health Care Equipment | $583M | — | — | 7 |
| 448 | NVCT | Nuvectis Pharma Inc | Biotechnology | $578M | — | — | 6 |
| 449 | CTNM | Contineum Therapeutics, Inc. Class A Common Stock | Pharmaceuticals | $578M | — | — | 5 |
| 450 | MYGN | Myriad Genetics Inc | Biotechnology | $551M | — | — | 12 |
| 451 | TLRY | Tilray Inc | Pharmaceuticals | $546M | — | — | 12 |
| 452 | ASMB | Assembly Biosciences Inc | Biotechnology | $543M | 342.5 | — | 12 |
| 453 | ARVN | Arvinas Inc | Pharmaceuticals | $534M | — | — | 10 |
| 454 | ANGO | AngioDynamics Inc | Health Care Equipment | $528M | — | — | 12 |
| 455 | MLAB | Mesa Laboratories Inc | Life Sciences Tools & Services | $528M | 79.0 | 0.7% | 12 |
| 456 | CTEV | Claritev Corporation | Health Care Equipment | $526M | — | — | 8 |
| 457 | PROK | ProKidney Corp. | Biotechnology | $526M | — | — | 7 |
| 458 | CLPT | Clearpoint Neuro Inc | Health Care Equipment | $525M | — | — | 12 |
| 459 | KIDS | Orthopediatrics Corp | Health Care Supplies | $522M | — | — | 12 |
| 460 | AQST | Aquestive Therapeutics Inc | Pharmaceuticals | $517M | — | — | 12 |
| 461 | MDRX | Veradigm Inc. | Health Care Technology | $517M | — | — | 12 |
| 462 | KYTX | Kyverna Therapeutics, Inc. Common Stock | Biotechnology | $516M | — | — | 5 |
| 463 | VALN | Valneva SE ADR | Biotechnology | $516M | — | — | 12 |
| 464 | CYH | Community Health Systems Inc | Health Care Facilities | $503M | 1.0 | — | 12 |
| 465 | EDIT | Editas Medicine Inc | Biotechnology | $500M | — | — | 12 |
| 466 | OCGN | Ocugen Inc | Biotechnology | $498M | — | — | 12 |
| 467 | ZURA | Zura Bio Limited Class A Ordinary Shares | Biotechnology | $493M | — | — | 5 |
| 468 | STRO | Sutro Biopharma | Biotechnology | $493M | — | — | 10 |
| 469 | NRC | National Research Corp | Health Care Services | $488M | 55.5 | 2.6% | 12 |
| 470 | VSTM | Verastem Inc | Biotechnology | $486M | — | — | 12 |
| 471 | CABA | Cabaletta Bio Inc | Biotechnology | $485M | — | — | 9 |
| 472 | PACB | Pacific Biosciences of California | Life Sciences Tools & Services | $485M | — | — | 12 |
| 473 | PRTA | Prothena Corporation plc | Biotechnology | $484M | — | — | 12 |
| 474 | CBIO | Crescent Biopharma, Inc. | Biotechnology | $478M | — | — | 12 |
| 475 | SOPH | Sophia Genetics SA | Health Care Equipment | $474M | — | — | 7 |
| 476 | VMD | Viemed Healthcare Inc | Health Care Equipment | $472M | 33.3 | — | 12 |
| 477 | OVID | Ovid Therapeutics Inc | Biotechnology | $470M | — | — | 12 |
| 478 | OFIX | Orthofix Medical Inc | Health Care Equipment | $470M | — | — | 12 |
| 479 | VREX | Varex Imaging Corp | Health Care Equipment | $466M | — | — | 12 |
| 480 | TENX | Tenax Therapeutics Inc | Biotechnology | $466M | — | — | 12 |
| 481 | BNTC | Benitec Biopharma Ltd ADR | Biotechnology | $461M | — | — | 12 |
| 482 | RZLT | Rezolute Inc | Biotechnology | $457M | — | — | 12 |
| 483 | ARTV | Artiva Biotherapeutics, Inc. Common Stock | Biotechnology | $457M | — | — | 6 |
| 484 | SGMT | Sagimet Biosciences Inc. Series A Common Stock | Biotechnology | $455M | — | — | 7 |
| 485 | DCTH | Delcath Systems Inc | Health Care Equipment | $449M | 1301.0 | — | 12 |
| 486 | CCCC | C4 Therapeutics Inc | Biotechnology | $449M | — | — | 8 |
| 487 | LRMR | Larimar Therapeutics Inc | Biotechnology | $445M | — | — | 12 |
| 488 | EPRX | Eupraxia Pharmaceuticals Inc. Common Stock | Biotechnology | $436M | — | — | 9 |
| 489 | CGC | Canopy Growth Corp | Pharmaceuticals | $436M | — | — | 12 |
| 490 | EOLS | Evolus Inc | Pharmaceuticals | $435M | — | — | 11 |
| 491 | SLN | Silence Therapeutics PLC | Biotechnology | $429M | — | — | 12 |
| 492 | AUTL | Autolus Therapeutics Ltd | Biotechnology | $428M | — | — | 12 |
| 493 | CCRN | Cross Country Healthcare Inc | Health Care Services | $427M | — | — | 12 |
| 494 | RCKT | Rocket Pharmaceuticals Inc | Biotechnology | $427M | — | — | 12 |
| 495 | PRTC | PureTech Health PLC | Biotechnology | $424M | — | — | 12 |
| 496 | CMPX | Compass Therapeutics Inc. | Biotechnology | $420M | — | — | 8 |
| 497 | XFOR | X4 Pharmaceuticals Inc | Biotechnology | $416M | — | — | 11 |
| 498 | EBS | Emergent Biosolutions Inc | Biotechnology | $415M | — | — | 12 |
| 499 | DMAC | DiaMedica Therapeutics Inc | Biotechnology | $413M | — | — | 12 |
| 500 | NNNN | Anbio Biotechnology Class A Ordinary Shares | Biotechnology | $412M | 72.2 | — | 5 |
| 501 | KMDA | Kamada | Biotechnology | $411M | 20.3 | 3.5% | 12 |
| 502 | UPB | Upstream Bio, Inc. | Biotechnology | $410M | — | — | 4 |
| 503 | PBYI | Puma Biotechnology Inc | Biotechnology | $407M | 16.7 | — | 12 |
| 504 | IPSC | Century Therapeutics Inc | Biotechnology | $406M | — | — | 9 |
| 505 | HELP | Cybin Inc. Common Stock | Pharmaceuticals | $404M | — | — | 10 |
| 506 | AVIR | Atea Pharmaceuticals Inc | Pharmaceuticals | $399M | — | — | 8 |
| 507 | ENTA | Enanta Pharmaceuticals Inc | Biotechnology | $398M | — | — | 12 |
| 508 | ABEO | Abeona Therapeutics Inc | Biotechnology | $398M | 7.3 | — | 12 |
| 509 | SLGC | Somalogic Inc | Health Care Equipment | $396M | — | — | 5 |
| 510 | TBRG | TruBridge Inc. | Health Care Technology | $394M | 90.5 | — | 12 |
| 511 | PRLD | Prelude Therapeutics Inc | Biotechnology | $383M | — | — | 8 |
| 512 | LXEO | Lexeo Therapeutics, Inc. Common Stock | Biotechnology | $378M | — | — | 6 |
| 513 | AUNA | Auna S.A. | Health Care Facilities | $378M | 18.9 | — | 9 |
| 514 | AKBA | Akebia Ther | Biotechnology | $376M | — | — | 12 |
| 515 | VNDA | Vanda Pharmaceuticals Inc | Biotechnology | $375M | — | — | 12 |
| 516 | SLP | Simulations Plus Inc | Health Care Technology | $369M | 45.6 | — | 12 |
| 517 | FENC | Fennec Pharmaceuticals Inc | Biotechnology | $364M | — | — | 12 |
| 518 | FATE | Fate Therapeutics Inc | Biotechnology | $361M | — | — | 12 |
| 519 | LAB | Standard Biotools Inc | Life Sciences Tools & Services | $360M | — | — | 12 |
| 520 | ELMD | Electromed Inc | Health Care Equipment | $354M | 36.6 | — | 12 |
| 521 | INDP | Indaptus Therapeutics Inc | Biotechnology | $350M | — | — | 12 |
| 522 | LYEL | Lyell Immunopharma Inc | Biotechnology | $350M | — | — | 7 |
| 523 | FHTX | Foghorn Therapeutics Inc | Biotechnology | $349M | — | — | 8 |
| 524 | ZNTL | Zentalis Pharmaceuticals Llc | Biotechnology | $347M | — | — | 8 |
| 525 | SNDL | SNDL Inc. | Pharmaceuticals | $341M | — | — | 10 |
| 526 | PALI | Palisade Bio Inc | Biotechnology | $341M | 16.3 | — | 12 |
| 527 | IRD | Opus Genetics, Inc. | Pharmaceuticals | $339M | — | — | 7 |
| 528 | CATX | Perspective Therapeutics Inc. | Health Care Equipment | $336M | — | — | 12 |
| 529 | AONC | American Oncology Network Inc. | Health Care Services | $336M | — | — | 6 |
| 530 | MASS | 908 Devices Inc | Health Care Equipment | $332M | — | — | 8 |
| 531 | OABI | OmniAb Inc. | Biotechnology | $332M | — | — | 7 |
| 532 | IMRX | Immuneering Corp | Biotechnology | $331M | — | — | 7 |
| 533 | AMRN | Amarin Corporation PLC | Biotechnology | $312M | — | — | 12 |
| 534 | ORGO | Organogenesis Holdings Inc | Biotechnology | $309M | — | — | 12 |
| 535 | BCYC | Bicycle Therapeutics Ltd | Biotechnology | $308M | — | — | 10 |
| 536 | NMRA | Neumora Therapeutics, Inc. | Pharmaceuticals | $306M | — | — | 7 |
| 537 | AIRS | Airsculpt Technologies Inc | Health Care Equipment | $305M | — | — | 7 |
| 538 | SBC | SBC Medical Group Holdings Incorporated | Health Care Services | $304M | 7.4 | — | 4 |
| 539 | IFRX | InflaRx N.V. | Biotechnology | $302M | — | — | 11 |
| 540 | CLLS | Cellectis SA | Biotechnology | $301M | — | — | 12 |
| 541 | ELDN | Eledon Pharmaceuticals Inc | Biotechnology | $297M | — | — | 12 |
| 542 | OSUR | OraSure Technologies Inc | Health Care Supplies | $296M | — | — | 12 |
| 543 | SABS | SAB Biotherapeutics Inc | Biotechnology | $292M | — | — | 7 |
| 544 | LCTX | Lineage Cell Therapeutics Inc | Biotechnology | $292M | — | — | 12 |
| 545 | GLSI | Greenwich Lifesciences Inc | Biotechnology | $291M | — | — | 9 |
| 546 | SGHT | Sight Sciences Inc | Health Care Equipment | $289M | — | — | 8 |
| 547 | TKNO | Alpha Teknova Inc | Biotechnology | $287M | — | — | 7 |
| 548 | ALXO | Alx Oncology Holdings | Biotechnology | $286M | — | — | 8 |
| 549 | TMCI | Treace Medical Concepts Inc | Health Care Equipment | $280M | — | — | 7 |
| 550 | RNAC | Cartesian Therapeutics Inc. | Biotechnology | $278M | — | — | 12 |
| 551 | MGNX | MacroGenics Inc | Biotechnology | $275M | — | — | 12 |
| 552 | NAGE | Niagen Bioscience, Inc. | Life Sciences Tools & Services | $272M | 17.1 | — | 12 |
| 553 | IKT | Inhibikase Therapeutics Inc | Biotechnology | $269M | — | — | 10 |
| 554 | SRZN | Surrozen Inc | Biotechnology | $269M | — | — | 7 |
| 555 | TRDA | Entrada Therapeutics Inc | Biotechnology | $269M | — | — | 7 |
| 556 | SENS | Senseonics Holdings, Inc. Common Stock | Health Care Supplies | $268M | — | — | 12 |
| 557 | GALT | Galectin Therapeutics Inc | Biotechnology | $267M | — | — | 12 |
| 558 | ACH | Accendra Health Inc | Not classified by GICS | $262M | — | — | 12 |
| 559 | ADAG | Adagene Inc | Biotechnology | $260M | — | — | 8 |
| 560 | SIGA | SIGA Technologies Inc | Pharmaceuticals | $257M | 12.8 | 0.0% | 12 |
| 561 | PROF | Profound Medical Corp | Health Care Equipment | $256M | — | — | 12 |
| 562 | TLSI | TriSalus Life Sciences Inc. | Health Care Equipment | $254M | — | — | 5 |
| 563 | PRQR | ProQR Therapeutics BV | Biotechnology | $244M | — | — | 12 |
| 564 | ACIU | AC Immune Ltd | Biotechnology | $243M | — | — | 12 |
| 565 | TARA | Protara Therapeutics Inc | Biotechnology | $243M | — | — | 12 |
| 566 | SLGL | Sol Gel Technologies Ltd | Pharmaceuticals | $242M | — | — | 12 |
| 567 | NAUT | Nautilus Biotechnology Inc | Biotechnology | $240M | — | — | 8 |
| 568 | OBIO | Orchestra BioMed Holdings Inc. | Biotechnology | $239M | — | — | 6 |
| 569 | KPTI | Karyopharm Therapeutics Inc | Biotechnology | $238M | — | — | 12 |
| 570 | CHRS | Coherus BioSciences Inc | Biotechnology | $238M | — | — | 12 |
| 571 | KROS | Keros Therapeutics Inc | Biotechnology | $234M | — | — | 8 |
| 572 | FULC | Fulcrum Therapeutics Inc | Pharmaceuticals | $233M | — | — | 9 |
| 573 | AVXL | Anavex Life Sciences Corp | Biotechnology | $232M | — | — | 12 |
| 574 | IVVD | Invivyd Inc. | Biotechnology | $231M | — | — | 6 |
| 575 | CAMP | CAMP4 THERAPEUTICS CORPORATION | Biotechnology | $229M | — | — | 12 |
| 576 | CGEN | Compugen | Life Sciences Tools & Services | $226M | 6.3 | — | 12 |
| 577 | DTIL | Precision BioSciences Inc | Biotechnology | $226M | — | — | 10 |
| 578 | LFMD | LifeMD Inc | Health Care Equipment | $224M | — | — | 12 |
| 579 | BDSX | Biodesix Inc | Biotechnology | $222M | — | — | 8 |
| 580 | CDXS | Codexis Inc | Life Sciences Tools & Services | $221M | — | — | 12 |
| 581 | NERV | Minerva Neurosciences Inc | Biotechnology | $220M | — | — | 12 |
| 582 | NBP | NovaBridge Biosciences | Biotechnology | $220M | — | — | 9 |
| 583 | SMTI | Sanara Medtech Inc | Health Care Equipment | $218M | 397.0 | — | 12 |
| 584 | UTMD | Utah Medical Products Inc | Health Care Supplies | $216M | 20.1 | 1.8% | 12 |
| 585 | QTTB | Q32 Bio Inc | Biotechnology | $213M | 5.1 | — | 10 |
| 586 | RNA | Atrium Therapeutics, Inc. Common Stock | Biotechnology | $213M | — | — | 11 |
| 587 | NKTX | Nkarta Inc | Biotechnology | $212M | — | — | 8 |
| 588 | KRRO | Korro Bio, Inc. | Biotechnology | $210M | — | — | 9 |
| 589 | VYGR | Voyager Therapeutics Inc | Biotechnology | $208M | — | — | 12 |
| 590 | ANIK | Anika Therapeutics Inc | Biotechnology | $208M | — | — | 12 |
| 591 | RXST | Rxsight Inc | Health Care Supplies | $205M | — | — | 7 |
| 592 | MSLE | Satellos Bioscience Inc. Common Stock | Not classified by GICS | $204M | — | — | 12 |
| 593 | FOCL | EDAP TMS S.A. | Not classified by GICS | $204M | — | — | 12 |
| 594 | IMUX | Immunic Inc | Biotechnology | $201M | — | — | 12 |
| 595 | PDEX | Pro-Dex Inc | Health Care Equipment | $201M | 17.3 | — | 12 |
| 596 | NGEN | NervGen Pharma Corp. | Not classified by GICS | $200M | — | — | 9 |
| 597 | TNXP | Tonix Pharmaceuticals Holding Corp | Biotechnology | $200M | — | — | 12 |
| 598 | ARCT | Arcturus Therapeutics Holdings Inc | Biotechnology | $198M | — | — | 12 |
| 599 | KRMD | Repro Med Systems Inc | Health Care Equipment | $197M | — | — | 12 |
| 600 | WHWK | Whitehawk Therapeutics, Inc. | Biotechnology | $196M | — | — | 7 |
| 601 | EMBC | Embecta Corp | Health Care Supplies | $192M | 1.7 | 18.9% | 7 |
| 602 | QSI | QuantumSi Inc | Biotechnology | $192M | — | — | 7 |
| 603 | CRBU | Caribou Biosciences Inc | Biotechnology | $191M | — | — | 7 |
| 604 | LUCD | Lucid Diagnostics Inc | Health Care Equipment | $191M | — | — | 8 |
| 605 | DERM | Journey Medical Corp | Biotechnology | $190M | — | — | 12 |
| 606 | ABOS | Acumen Pharmaceuticals Inc | Biotechnology | $190M | — | — | 7 |
| 607 | OTLK | OUTLOOK THERAPEUTICS INC | Biotechnology | $190M | — | — | 12 |
| 608 | TNYA | Tenaya Therapeutics Inc | Biotechnology | $189M | — | — | 7 |
| 609 | HUMA | Humacyte Inc | Biotechnology | $187M | — | — | 7 |
| 610 | INFU | InfuSystems Holdings Inc | Health Care Services | $186M | 25.0 | — | 12 |
| 611 | PLX | Protalix Biotherapeutics Inc | Biotechnology | $186M | 12.2 | — | 12 |
| 612 | APYX | Apyx Medical Inc | Health Care Equipment | $184M | — | — | 12 |
| 613 | EQ | Equillium Inc | Biotechnology | $184M | — | — | 9 |
| 614 | MDWD | Mediwound Ltd | Pharmaceuticals | $184M | — | — | 12 |
| 615 | CNTN | Canton Strategic Holdings, Inc. | Not classified by GICS | $184M | — | — | 7 |
| 616 | ACOG | Alpha Cognition Inc | Biotechnology | $183M | — | — | 8 |
| 617 | QTRX | Quanterix Corp | Life Sciences Tools & Services | $183M | — | — | 11 |
| 618 | CRBP | Corbus Pharmaceuticals Holding | Biotechnology | $179M | — | — | 12 |
| 619 | NRXP | NRX Pharmaceuticals Inc | Biotechnology | $179M | — | — | 9 |
| 620 | ALEC | Alector Inc | Biotechnology | $179M | — | — | 10 |
| 621 | INGN | Inogen Inc | Health Care Equipment | $177M | — | — | 12 |
| 622 | OWLT | Owlet Inc | Health Care Equipment | $177M | — | — | 7 |
| 623 | LFCR | Lifecore Biomedical Inc. | Biotechnology | $176M | — | — | 12 |
| 624 | LENZ | LENZ Therapeutics Inc | Biotechnology | $175M | — | — | 7 |
| 625 | OKUR | OnKure Therapeutics, Inc. | Biotechnology | $173M | — | — | 6 |
| 626 | NYXH | Nyxoah | Health Care Equipment | $171M | — | — | 9 |
| 627 | HCAT | Health Catalyst Inc | Health Care Technology | $169M | — | — | 9 |
| 628 | PYXS | Pyxis Oncology Inc | Biotechnology | $169M | — | — | 7 |
| 629 | IPHA | Innate Pharma | Biotechnology | $168M | — | — | 12 |
| 630 | MENS | Jyong Biotech Ltd. Ordinary Shares | Biotechnology | $168M | — | — | 6 |
| 631 | ACB | Aurora Cannabis Inc | Pharmaceuticals | $168M | — | — | 12 |
| 632 | ANTX | AN2 Therapeutics Inc | Biotechnology | $167M | — | — | 7 |
| 633 | AMWL | American Well Corp | Health Care Equipment | $166M | — | — | 8 |
| 634 | ORMP | Oramed Pharmaceuticals Inc | Pharmaceuticals | $165M | 1.6 | 0.0% | 12 |
| 635 | ADCT | ADC Therapeutics SA | Biotechnology | $164M | — | — | 9 |
| 636 | STXS | Stereotaxis Inc | Health Care Equipment | $164M | — | — | 12 |
| 637 | IMDX | Insight Molecular Diagnostics Inc. | Health Care Equipment | $164M | — | — | 12 |
| 638 | CBUS | Cibus Global LLC | Biotechnology | $164M | — | — | 11 |
| 639 | EDAP | EDAP TMS SA | Health Care Equipment | $162M | — | — | 12 |
| 640 | MIST | Milestone Pharmaceuticals Inc | Pharmaceuticals | $159M | — | — | 9 |
| 641 | PEPG | PepGen Ltd | Biotechnology | $159M | — | — | 7 |
| 642 | CNTB | Connect Biopharma Holdings Ltd | Biotechnology | $158M | — | — | 8 |
| 643 | TLSA | Tiziana Life Sciences Ltd | Biotechnology | $157M | — | — | 12 |
| 644 | KZIA | Kazia Therapeutics Ltd ADR | Biotechnology | $155M | — | — | 12 |
| 645 | CUE | Cue Biopharma | Biotechnology | $154M | — | — | 11 |
| 646 | HURA | TuHURA Biosciences Inc | Biotechnology | $152M | — | — | 12 |
| 647 | ASRT | Assertio Therapeutics Inc | Pharmaceuticals | $152M | — | — | 12 |
| 648 | YDES | YD Bio Ltd | Not classified by GICS | $152M | — | — | 6 |
| 649 | MOLN | Molecular Partners AG ADR | Biotechnology | $151M | — | — | 12 |
| 650 | CVRX | CVRx Inc | Health Care Equipment | $144M | — | — | 7 |
| 651 | EMPG | Empro Group Inc. Ordinary shares | Not classified by GICS | $143M | 192.9 | — | 4 |
| 652 | UNCY | Unicycive Therapeutics Inc | Biotechnology | $143M | — | — | 8 |
| 653 | MXCT | MaxCyte Inc | Health Care Equipment | $142M | — | — | 12 |
| 654 | AGEN | Agenus Inc | Biotechnology | $140M | 1.6 | — | 12 |
| 655 | ARMP | Armata Pharmaceuticals Inc | Biotechnology | $138M | — | — | 12 |
| 656 | SPRB | Spruce Biosciences, Inc. Common Stock | Biotechnology | $138M | — | — | 8 |
| 657 | OGI | OrganiGram Holdings Inc | Pharmaceuticals | $136M | — | — | 12 |
| 658 | BGM | Qilian International Holding Group Limited | Pharmaceuticals | $134M | — | — | 8 |
| 659 | GNLX | Genelux Corporation Common Stock | Biotechnology | $134M | — | — | 7 |
| 660 | VXRT | Vaxart Inc | Biotechnology | $133M | 3.4 | — | 12 |
| 661 | AARD | Aardvark Therapeutics, Inc. Common Stock | Pharmaceuticals | $133M | — | — | 4 |
| 662 | VTVT | vTv Therapeutics Inc | Biotechnology | $132M | — | — | 12 |
| 663 | VANI | Vivani Medical Inc. | Biotechnology | $128M | — | — | 12 |
| 664 | JYNT | The Joint Corp | Health Care Facilities | $128M | 99.9 | — | 12 |
| 665 | PMN | ProMIS Neurosciences Inc. | Biotechnology | $128M | — | — | 12 |
| 666 | ENGN | enGene Holdings Inc. Common Stock | Biotechnology | $127M | — | — | 6 |
| 667 | MBOT | Microbot Medical Inc | Health Care Equipment | $127M | — | — | 12 |
| 668 | LIXT | Lixte Biotechnology Holdings Inc | Biotechnology | $125M | — | — | 12 |
| 669 | RCEL | Avita Medical Ltd | Biotechnology | $125M | — | — | 12 |
| 670 | ALDX | Aldeyra The | Biotechnology | $125M | — | — | 12 |
| 671 | BNR | Burning Rock Biotech Ltd | Biotechnology | $123M | — | — | 9 |
| 672 | COYA | Coya Therapeutics, Inc. Common Stock | Biotechnology | $123M | — | — | 6 |
| 673 | SPRO | Spero Therapeutics Inc | Biotechnology | $123M | 8.2 | — | 11 |
| 674 | STIM | Neuronetics Inc | Health Care Equipment | $122M | — | — | 10 |
| 675 | GUTS | Fractyl Health, Inc. Common Stock | Health Care Equipment | $121M | — | — | 7 |
| 676 | OPRX | OPTIMIZERx Corp | Health Care Technology | $120M | 17.8 | — | 12 |
| 677 | ALTS | ALT5 Sigma Corporation | Pharmaceuticals | $120M | — | — | 6 |
| 678 | SEER | Seer Inc | Life Sciences Tools & Services | $119M | — | — | 8 |
| 679 | CRDL | Cardiol Therapeutics Inc Class A | Biotechnology | $116M | — | — | 9 |
| 680 | NTHI | NeOnc Technologies Holdings, Inc. Common Stock | Pharmaceuticals | $116M | — | — | 5 |
| 681 | FBIO | Fortress Biotech Inc | Biotechnology | $110M | 1.0 | — | 12 |
| 682 | BDTX | Black Diamond Therapeutics Inc | Biotechnology | $109M | — | — | 9 |
| 683 | HYPR | Hyperfine Inc | Health Care Equipment | $108M | — | — | 7 |
| 684 | VRCA | Verrica Pharmaceuticals Inc | Pharmaceuticals | $108M | — | — | 10 |
| 685 | XGN | Exagen Inc | Biotechnology | $108M | — | — | 12 |
| 686 | ONCY | Oncolytics Biotech Inc | Biotechnology | $106M | — | — | 12 |
| 687 | KLRS | Kalaris Therapeutics, Inc. | Biotechnology | $106M | — | — | 8 |
| 688 | KEQU | Kewaunee Scientific Corporation | Health Care Equipment | $105M | 11.4 | — | 12 |
| 689 | ANIX | Anixa Biosciences Inc | Biotechnology | $104M | — | — | 12 |
| 690 | SNWV | SANUWAVE Health, Inc. Common Stock | Health Care Equipment | $103M | 11.7 | — | 12 |
| 691 | HSDT | Helius Medical Technologies Inc Class A | Health Care Equipment | $102M | 0.0 | — | 12 |
| 692 | PYPD | PolyPid | Biotechnology | $100M | — | — | 12 |
| 693 | ICCC | ImmuCell Corporation | Biotechnology | $98.5M | — | — | 12 |
| 694 | ATHE | Alterity Therapeutics Ltd | Biotechnology | $98.4M | — | — | 12 |
| 695 | CGTX | Cognition Therapeutics Inc | Biotechnology | $97.6M | — | — | 7 |
| 696 | INO | Inovio Pharmaceuticals Inc | Biotechnology | $97.1M | — | — | 12 |
| 697 | CCLD | CareCloud, Inc. | Health Care Equipment | $96.9M | 17.5 | — | 12 |
| 698 | BMEA | Biomea Fusion Inc | Biotechnology | $95.4M | — | — | 7 |
| 699 | RANI | Rani Therapeutics Holdings Inc | Biotechnology | $94.5M | — | — | 7 |
| 700 | PTHS | Pelthos Therapeutics Inc. | Pharmaceuticals | $92.8M | — | — | 6 |
| 701 | ELTX | Elicio Therapeutics Inc. | Pharmaceuticals | $91.4M | — | — | 10 |
| 702 | RLYB | Rallybio Corp | Biotechnology | $91.2M | — | — | 7 |
| 703 | CRDF | Cardiff Oncology Inc | Biotechnology | $90.9M | — | — | 12 |
| 704 | LONA | LeonaBio, Inc. | Pharmaceuticals | $90.2M | — | — | 8 |
| 705 | CPIX | Cumberland Pharmaceuticals Inc | Pharmaceuticals | $88.8M | — | — | 12 |
| 706 | OKYO | OKYO Pharma Ltd ADR | Biotechnology | $88.7M | — | — | 12 |
| 707 | DH | Definitive Healthcare Corp | Health Care Technology | $88.2M | — | — | 7 |
| 708 | ATRA | Atara Biotherapeutics Inc | Biotechnology | $87.9M | — | — | 12 |
| 709 | GOSS | Gossamer Bio Inc | Biotechnology | $85.5M | — | — | 10 |
| 710 | RNTX | Rein Therapeutics Inc | Biotechnology | $85.4M | — | — | 6 |
| 711 | TELO | Telomir Pharmaceuticals, Inc. Common Stock | Pharmaceuticals | $84.9M | — | — | 5 |
| 712 | NRXS | Neuraxis, Inc. | Biotechnology | $84M | — | — | 6 |
| 713 | ACRV | Acrivon Therapeutics, Inc. Common Stock | Biotechnology | $83.9M | — | — | 6 |
| 714 | AGPU | Axe Compute Inc. | Health Care Equipment | $83.8M | — | — | 12 |
| 715 | ODYS | Odysight.ai Inc. Common Stock | Health Care Equipment | $82.9M | — | — | 12 |
| 716 | BTMD | biote Corp | Health Care Equipment | $82.8M | 5.4 | — | 7 |
| 717 | ACET | Adicet Bio Inc | Health Care Distributors | $82.5M | — | — | 12 |
| 718 | OM | Outset Medical Inc | Health Care Equipment | $82.1M | — | — | 8 |
| 719 | ENTX | Entera Bio Ltd | Biotechnology | $81.6M | — | — | 11 |
| 720 | MAIA | MAIA Biotechnology Inc. | Biotechnology | $80.9M | — | — | 7 |
| 721 | CSBR | Champions Oncology Inc | Life Sciences Tools & Services | $80.8M | — | — | 12 |
| 722 | KG | Kestrel Group, Ltd. | Pharmaceuticals | $80.3M | 1.9 | — | 12 |
| 723 | CLNN | Clene Inc. | Biotechnology | $80.1M | — | — | 9 |
| 724 | ANVS | Annovis Bio Inc | Biotechnology | $79.1M | — | — | 12 |
| 725 | HRTX | Heron Therapeuti | Biotechnology | $78.4M | — | — | 12 |
| 726 | STSS | Sharps Technology Inc | Health Care Equipment | $77.9M | — | — | 8 |
| 727 | SERA | Sera Prognostics Inc | Biotechnology | $77.1M | — | — | 7 |
| 728 | GANX | Gain Therapeutics Inc | Biotechnology | $76.8M | — | — | 8 |
| 729 | IBIO | iBio, Inc. Common Stock | Biotechnology | $75M | — | — | 12 |
| 730 | CYPH | Cypherpunk Technologies Inc. | Biotechnology | $74.8M | — | — | 12 |
| 731 | LNSR | LENSAR Inc | Health Care Equipment | $73.8M | — | — | 8 |
| 732 | TLPH | Talphera Inc. | Pharmaceuticals | $73.4M | — | — | 12 |
| 733 | NNOX | Nano X Imaging Ltd | Health Care Equipment | $73.1M | — | — | 8 |
| 734 | GNTA | Genenta Science SpA ADR | Biotechnology | $72.3M | — | — | 7 |
| 735 | TCRX | Tscan Therapeutics Inc | Biotechnology | $71.2M | — | — | 7 |
| 736 | XBIT | XBiotech Inc | Biotechnology | $69.8M | — | — | 12 |
| 737 | PLRX | Pliant Therapeutics Inc | Biotechnology | $69.4M | — | — | 9 |
| 738 | MNOV | MediciNova Inc | Biotechnology | $68.4M | — | — | 12 |
| 739 | FORA | Forian Inc | Health Care Equipment | $67.8M | — | — | 7 |
| 740 | EDSA | Edesa Biotech Inc | Biotechnology | $67.5M | — | — | 12 |
| 741 | OSTX | OS Therapies Incorporated | Biotechnology | $66.8M | — | — | 6 |
| 742 | SCLX | Scilex Holding Company | Pharmaceuticals | $66.7M | — | — | 7 |
| 743 | IMA | ImageneBio, Inc. | Biotechnology | $66.7M | — | — | 8 |
| 744 | CING | Cingulate Inc | Biotechnology | $66.1M | — | — | 7 |
| 745 | PMVP | Pmv Pharmaceuticals Inc | Biotechnology | $66.1M | — | — | 8 |
| 746 | NAKA | Nakamoto Inc. | Health Care Services | $66M | — | — | 5 |
| 747 | CTOR | Citius Oncology, Inc. | Life Sciences Tools & Services | $65.3M | — | — | 5 |
| 748 | LUNG | Pulmonx Corp | Health Care Equipment | $65M | — | — | 12 |
| 749 | EXOZ | eXoZymes, Inc. | Biotechnology | $64.7M | — | — | 5 |
| 750 | XTNT | Xtant Medical Holdings Inc | Health Care Supplies | $62.1M | 44.3 | — | 12 |
| 751 | IMMP | Immutep Ltd ADR | Biotechnology | $61.7M | — | — | 12 |
| 752 | DXR | Daxor Corporation | Health Care Equipment | $61.5M | 6.4 | — | 12 |
| 753 | ZTEK | ZEN Graphene Solutions Ltd | Health Care Equipment | $60.3M | — | — | 12 |
| 754 | CNTX | Context Therapeutics Inc | Pharmaceuticals | $60M | — | — | 9 |
| 755 | XLO | Xilio Development Inc | Biotechnology | $59.8M | — | — | 7 |
| 756 | BYSI | BeyondSpring Inc | Biotechnology | $59.2M | — | — | 12 |
| 757 | MCRB | Seres Therapeutics Inc | Biotechnology | $59.2M | — | — | 12 |
| 758 | DCGO | DocGo Inc | Health Care Equipment | $59M | — | — | 7 |
| 759 | FLNA | Filana Therapeutics, Inc. | Not classified by GICS | $57M | — | — | 5 |
| 760 | INCR | InterCure Ltd. | Biotechnology | $55.4M | — | — | 12 |
| 761 | INKT | Mink Therapeutics Inc | Biotechnology | $55M | — | — | 7 |
| 762 | MDAI | Spectral AI Inc. | Health Care Equipment | $54.7M | — | — | 6 |
| 763 | ECOR | Electrocore LLC | Health Care Equipment | $54.7M | — | — | 10 |
| 764 | POCI | Precision Optics Corporation, Inc. Common stock | Health Care Equipment | $54.5M | — | — | 12 |
| 765 | BOLD | Boundless Bio, Inc. Common Stock | Biotechnology | $54.2M | — | — | 8 |
| 766 | KZR | Kezar Life Sciences Inc | Biotechnology | $53.9M | — | — | 10 |
| 767 | ATYR | aTyr Pharma, Inc. | Biotechnology | $53.7M | — | — | 12 |
| 768 | DRIO | DarioHealth Corp | Health Care Technology | $52.8M | — | — | 12 |
| 769 | COCH | Envoy Medical Inc. | Health Care Equipment | $52.6M | — | — | 6 |
| 770 | TIL | Instil Bio Inc. | Biotechnology | $52.2M | — | — | 7 |
| 771 | MREO | Mereo BioPharma Group PLC ADR | Biotechnology | $51.7M | — | — | 11 |
| 772 | INMB | INmune Bio Inc | Biotechnology | $51.6M | — | — | 11 |
| 773 | SRTS | Sensus Healthcare Inc | Health Care Equipment | $50.2M | — | — | 12 |
| 774 | HSCSW | Heart Test Laboratories Inc. Warrant | Health Care Equipment | — | — | — | 7 |
| 775 | IINNW | Inspira Technologies Oxy B.H.N. Ltd. Warrant | Health Care Equipment | — | — | — | 8 |
| 776 | MSPRW | MSP Recovery, Inc. | Health Care Technology | — | — | — | 5 |
| 777 | SABSW | SAB Biotherapeutics Inc | Biotechnology | — | 0.0 | — | 7 |