Praxis Precision Medicines, Inc.
PRAXFigures shown here come from public SEC filings. Dates beside each section show the available history.
How Praxis Precision Medicines, Inc. Makes Money
Follow each dollar of revenue through to what shareholders keep.
From revenue to net income
Pick a year or quarter. Each band's width is its dollar amount.
Financial Summary
Choose a year or quarter, compare it with the same period a year earlier, and open any row for its full filing history.
Loading financial history…
SEC filings supply these figures; updates after the dates shown are not included. This page includes 6 annual periods. The latest annual period ends Dec 31, 2025. The latest insider filing shown is dated Jun 26, 2026. The latest institutional report shown is dated Jun 30, 2023; other ownership filings may exist.
Ownership
Who holds the shares, as reported in SEC ownership filings.
Reported 13F positions
Each row shows what a filer reported for one date, not a current position. The link opens that filing.
| Filer | Report date | Shares | Value | Filing |
|---|---|---|---|---|
| NEW YORK STATE COMMON RETIREMENT FUND | 2023-06-30 | 327 | $376 | SEC filing |
| NEW YORK STATE COMMON RETIREMENT FUND | 2023-03-31 | 5,832 | $4.72K | SEC filing |
| BARCLAYS PLC | 2023-03-31 | 24,167 | $19.6K | SEC filing |
| Voya Investment Management LLC | 2023-03-31 | 19,216 | $15.5K | SEC filing |
| BARCLAYS PLC | 2022-12-31 | 10,539 | Not shown | SEC filing |
| NEW YORK STATE COMMON RETIREMENT FUND | 2022-12-31 | 26,332 | Not shown | SEC filing |
| Voya Investment Management LLC | 2022-12-31 | 18,069 | Not shown | SEC filing |
- Each value is checked against Praxis Precision Medicines, Inc.'s share prices from within about three months of its report date (insiders' Form 4 trades and the latest close).
- Value not shown for 3 rows: the value per share could not be confirmed against the share prices on file from within three months of the report date.
Filer report history
Two reports per filer, as filed. No change is calculated, because the data on file cannot confirm that both reports describe the same security.
- NEW YORK STATE COMMON RETIREMENT FUND: 5,832 shares reported 2023-03-31; 327 shares reported 2023-06-30.
- NEW YORK STATE COMMON RETIREMENT FUND: 26,332 shares reported 2022-12-31; 5,832 shares reported 2023-03-31.
- Voya Investment Management LLC: 18,069 shares reported 2022-12-31; 19,216 shares reported 2023-03-31.
- BARCLAYS PLC: 10,539 shares reported 2022-12-31; 24,167 shares reported 2023-03-31.
Unusually large insider trades
Each trade is compared with the other insider trades of the same kind in the same security among Praxis Precision Medicines, Inc.'s recent filings on file. Size alone is context, not a prediction or evidence of improper trading.
- 2025-11-20 · Mastrocola Lauren: Larger than 18 of the 20 other insider sales of Common Stock on file. SEC filing
- 2025-11-20 · Nemiroff Alex: Larger than 19 of the 20 other insider sales of Common Stock on file. SEC filing
- 2021-10-06 · SCHWARZMAN STEPHEN A: Larger than all 20 other insider sales of Common Stock on file. SEC filing
Independent insiders buying near the same time
- 2022-06-09–2022-06-16: 3 event(s) across 3 owner(s) — A cluster counts independent reporting owners that reported purchases within a set time. Co-filers and declared affiliates count once, and duplicate reports of the same event count once. ( filing , filing , filing )
- 2022-06-08–2022-06-13: 4 event(s) across 4 owner(s) — A cluster counts independent reporting owners that reported purchases within a set time. Co-filers and declared affiliates count once, and duplicate reports of the same event count once. ( filing , filing , filing , filing )
Purchases & sales (open market or private)
| Security | Code | Price | Filing | |||
|---|---|---|---|---|---|---|
| 2026-06-24 | DeSimone Jill · Director | Common Stock | S — Open market or private sale | −1,279 | 314.90 | SEC filing |
| 2026-06-24 | DeSimone Jill · Director | Common Stock | S — Open market or private sale | −320 | 305.31 | SEC filing |
| 2026-06-24 | DeSimone Jill · Director | Common Stock | S — Open market or private sale | −10 | 301.44 | SEC filing |
| 2026-06-24 | DeSimone Jill · Director | Common Stock | S — Open market or private sale | −504 | 313.66 | SEC filing |
| 2026-06-24 | DeSimone Jill · Director | Common Stock | S — Open market or private sale | −2,854 | 311.91 | SEC filing |
| 2026-06-24 | DeSimone Jill · Director | Common Stock | S — Open market or private sale | −1,240 | 308.24 | SEC filing |
| 2026-06-24 | DeSimone Jill · Director | Common Stock | S — Open market or private sale | −120 | 303.13 | SEC filing |
| 2026-06-24 | DeSimone Jill · Director | Common Stock | S — Open market or private sale | −683 | 306.77 | SEC filing |
Showing 8 of 20 rows
Grants, exercises, tax & gifts
| Security | Code | Filing | |||
|---|---|---|---|---|---|
| 2026-06-24 | DeSimone Jill · Director | Stock Option (Right to Buy) | M — Exercise or conversion of derivative security | −8,566 | SEC filing |
| 2026-06-24 | DeSimone Jill · Director | Common Stock | M — Exercise or conversion of derivative security | +3,034 | SEC filing |
| 2026-06-24 | DeSimone Jill · Director | Common Stock | M — Exercise or conversion of derivative security | +8,566 | SEC filing |
| 2026-06-24 | DeSimone Jill · Director | Stock Option (Right to Buy) | M — Exercise or conversion of derivative security | −3,034 | SEC filing |
| 2026-06-10 | Arbuckle Stuart A · Director | Stock Option (Right to Buy) | A — Grant, award, or other acquisition | +648 | SEC filing |
| 2026-06-10 | KINDLER JEFFREY B · Director | Stock Option (Right to Buy) | A — Grant, award, or other acquisition | +648 | SEC filing |
| 2026-06-10 | KINDLER JEFFREY B · Director | Common Stock | A — Grant, award, or other acquisition | +1,371 | SEC filing |
| 2026-06-10 | DeSimone Jill · Director | Common Stock | A — Grant, award, or other acquisition | +1,371 | SEC filing |
Showing 8 of 31 rows
These tables describe filed transactions, not current holdings. Prices are shown as filed; a currency is added only when the filing's data names one. Amended and possible duplicate rows are left out of size comparisons and transaction groups.