Spruce Biosciences, Inc.
SPRBAs of the close on Sep 25, 2026
Price
$48.72
Market cap
—
The cover-page share count does not match the latest report's share count
P/E (diluted TTM)
—
A per-share figure for one of the last four quarters is not shown, so no four-quarter total is given
EPS (TTM)
—
A per-share figure for one of the last four quarters is not shown, so no four-quarter total is given
Dividend yield
—
Dividend records do not yet cover the latest payments
Figures shown here come from public SEC filings. Dates beside each section show the available history.
How Spruce Biosciences, Inc. Makes Money
Follow each dollar of revenue through to what shareholders keep.
From revenue to net income
Pick a year or quarter. Each band's width is its dollar amount.
Source: Spruce Biosciences, Inc. — 10-K filed Mar 9, 2026
Financial Summary
Choose a year or quarter, compare it with the same period a year earlier, and open any row for its full filing history.
Loading financial history…
SEC filings supply these figures; updates after the dates shown are not included. This page includes 5 annual periods. The latest annual period ends Dec 31, 2025. The latest insider filing shown is dated May 26, 2026. The latest institutional report shown is dated Jun 30, 2025; other ownership filings may exist.
Ownership
Who holds the shares, as reported in SEC ownership filings.
Reported 13F positions
Each row shows what a filer reported for one date, not a current position. The link opens that filing.
| Filer | Report date | Shares | Value | Filing |
|---|---|---|---|---|
| ACADIAN ASSET MANAGEMENT LLC | 2025-06-30 | 1,045,828 | Not shown | SEC filing |
| CALDWELL SUTTER CAPITAL, INC. | 2025-06-30 | 1,000 | Not shown | SEC filing |
| Ikarian Capital, LLC | 2025-06-30 | 1,000,000 | Not shown | SEC filing |
| Carlyle Group Inc. | 2025-03-31 | 2,896,518 | Not shown | SEC filing |
| XTX Topco Ltd | 2025-03-31 | 41,217 | Not shown | SEC filing |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 2025-03-31 | 0 | $0 | SEC filing |
| CALDWELL SUTTER CAPITAL, INC. | 2025-03-31 | 1,000 | Not shown | SEC filing |
| Shay Capital LLC | 2025-03-31 | 38,119 | Not shown | SEC filing |
| Virtu Financial LLC | 2025-03-31 | 39,426 | Not shown | SEC filing |
| BOOTHBAY FUND MANAGEMENT, LLC | 2025-03-31 | 288,800 | Not shown | SEC filing |
| NORTHERN TRUST CORP | 2025-03-31 | 32,721 | Not shown | SEC filing |
| ADAR1 Capital Management, LLC | 2025-03-31 | 403,716 | Not shown | SEC filing |
| JPMORGAN CHASE & CO | 2025-03-31 | 65 | Not shown | SEC filing |
| MORGAN STANLEY | 2025-03-31 | 7,396 | Not shown | SEC filing |
| BANK OF AMERICA CORP /DE/ | 2025-03-31 | 233 | Not shown | SEC filing |
| Ikarian Capital, LLC | 2025-03-31 | 1,000,000 | Not shown | SEC filing |
| GEODE CAPITAL MANAGEMENT, LLC | 2025-03-31 | 276,708 | Not shown | SEC filing |
| Tower Research Capital LLC (TRC) | 2025-03-31 | 4,697 | Not shown | SEC filing |
| Marex Group plc | 2025-03-31 | 14,800 | Not shown | SEC filing |
| GROUP ONE TRADING LLC | 2025-03-31 | 1,153 | Not shown | SEC filing |
- Each value is checked against Spruce Biosciences, Inc.'s share prices from within about three months of its report date (insiders' Form 4 trades and the latest close).
- Value not shown for 19 rows: no share price from within three months of their report dates is on file, so they could not be checked.
Filer report history
Two reports per filer, as filed. No change is calculated, because the data on file cannot confirm that both reports describe the same security.
- Ikarian Capital, LLC: 1,000,000 shares reported 2025-03-31; 1,000,000 shares reported 2025-06-30.
- CALDWELL SUTTER CAPITAL, INC.: 1,000 shares reported 2025-03-31; 1,000 shares reported 2025-06-30.
- ACADIAN ASSET MANAGEMENT LLC: 1,045,828 shares reported 2025-03-31; 1,045,828 shares reported 2025-06-30.
- Ikarian Capital, LLC: 1,000,000 shares reported 2024-12-31; 1,000,000 shares reported 2025-03-31.
- CALDWELL SUTTER CAPITAL, INC.: 1,000 shares reported 2024-12-31; 1,000 shares reported 2025-03-31.
- ACADIAN ASSET MANAGEMENT LLC: 1,045,828 shares reported 2024-12-31; 1,045,828 shares reported 2025-03-31.
- TWO SIGMA INVESTMENTS, LP: 20,616 shares reported 2024-12-31; 20,545 shares reported 2025-03-31.
- RENAISSANCE TECHNOLOGIES LLC: 405,900 shares reported 2024-12-31; 382,900 shares reported 2025-03-31.
- JANE STREET GROUP, LLC: 15,658 shares reported 2024-09-30; 37,429 shares reported 2025-03-31.
- STATE STREET CORP: 60,700 shares reported 2024-12-31; 60,700 shares reported 2025-03-31.
- Lion Point Capital, LP: 75,000 shares reported 2024-12-31; 75,000 shares reported 2025-03-31.
- BlackRock, Inc.: 124,734 shares reported 2024-12-31; 124,734 shares reported 2025-03-31.
Showing the 12 most recent filer reports.
11 filers have only one report here.
Independent insiders buying near the same time
- 2023-02-16–2023-02-16: 2 event(s) across 2 owner(s) — A cluster counts independent reporting owners that reported purchases within a set time. Co-filers and declared affiliates count once, and duplicate reports of the same event count once. ( filing , filing )
- 2020-10-14–2020-10-14: 5 event(s) across 5 owner(s) — A cluster counts independent reporting owners that reported purchases within a set time. Co-filers and declared affiliates count once, and duplicate reports of the same event count once. ( filing , filing , filing , filing , filing )
Purchases & sales (open market or private)
| Security | Code | Price | Filing | |||
|---|---|---|---|---|---|---|
| 2025-10-06 | Parkman Healthcare Partners LLC · 10% owner | Common Stock, $0.001 par value per share | P — Open market or private purchase | +256 | 17.91 | SEC filing |
| 2025-10-06 | Parkman Healthcare Partners LLC · 10% owner | Common Stock, $0.001 par value per share | S — Open market or private sale | −25 | 17.46 | SEC filing |
| 2025-10-06 | Parkman Healthcare Partners LLC · 10% owner | Common Stock, $0.001 par value per share | S — Open market or private sale | −232 | 19.33 | SEC filing |
| 2024-03-21 | Novo Holdings A/S · 10% owner | COMMON STOCK | S — Open market or private sale | −465,021 | 0.75 | SEC filing |
| 2024-03-20 | Novo Holdings A/S · 10% owner | COMMON STOCK | S — Open market or private sale | −359,979 | 0.73 | SEC filing |
| 2024-03-19 | Novo Holdings A/S · 10% owner | COMMON STOCK | S — Open market or private sale | −593,000 | 0.76 | SEC filing |
| 2024-03-18 | Novo Holdings A/S · 10% owner | COMMON STOCK | S — Open market or private sale | −842,020 | 0.77 | SEC filing |
| 2024-03-14 | Novo Holdings A/S · 10% owner | COMMON STOCK | S — Open market or private sale | −1,912,316 | 0.89 | SEC filing |
Showing 8 of 20 rows
Grants, exercises, tax & gifts
| Security | Code | Filing | |||
|---|---|---|---|---|---|
| 2026-05-21 | GREY MICHAEL G · Executive Chairman | Stock Option (Right to Buy) | A — Grant, award, or other acquisition | +1,700 | SEC filing |
| 2026-05-21 | SPIEGELMAN DANIEL K · Director | Stock Option (Right to Buy) | A — Grant, award, or other acquisition | +1,700 | SEC filing |
| 2026-05-21 | Barretto-Ko Percival · Director | Stock Option (Right to Buy) | A — Grant, award, or other acquisition | +1,700 | SEC filing |
| 2026-05-21 | SIMPSON CAMILLA V · Director | Stock Option (Right to Buy) | A — Grant, award, or other acquisition | +1,700 | SEC filing |
| 2026-05-21 | Walbert Keli · Director | Stock Option (Right to Buy) | A — Grant, award, or other acquisition | +1,700 | SEC filing |
| 2026-03-09 | Hooks Corwin Dale · Chief Commercial Officer | Restricted Stock Units | A — Grant, award, or other acquisition | +11,000 | SEC filing |
| 2025-12-31 | Szwarcberg Javier B. · CHIEF EXECUTIVE OFFICER | Common Stock | A — Grant, award, or other acquisition | +4,690 | SEC filing |
| 2025-12-15 | Szwarcberg Javier B. · CHIEF EXECUTIVE OFFICER | Restricted Stock Units | M — Exercise or conversion of derivative security | −1,480 | SEC filing |
Showing 8 of 30 rows
Other activity
| Security | Code | Filing | |||
|---|---|---|---|---|---|
| 2025-12-11 | GREY MICHAEL G · Executive Chairman | Stock Option (Right to Buy) | D — Disposition to the issuer | −1,499 | SEC filing |
| 2025-12-11 | SIMPSON CAMILLA V · Director | Stock Option (right to buy) | D — Disposition to the issuer | −133 | SEC filing |
| 2025-12-11 | SPIEGELMAN DANIEL K · Director | Stock Option (right to buy) | D — Disposition to the issuer | −88 | SEC filing |
| 2025-12-11 | GREY MICHAEL G · Executive Chairman | Stock Option (Right to Buy) | D — Disposition to the issuer | −387 | SEC filing |
| 2025-12-11 | SIMPSON CAMILLA V · Director | Stock Option (Right to Buy) | D — Disposition to the issuer | −400 | SEC filing |
| 2025-12-11 | SIMPSON CAMILLA V · Director | Stock Option (Right to Buy) | D — Disposition to the issuer | −309 | SEC filing |
| 2025-12-11 | Gharib Samir M. · PRESIDENT AND CFO | Stock Option (Right to Buy) | D — Disposition to the issuer | −733 | SEC filing |
| 2025-12-11 | GREY MICHAEL G · Executive Chairman | Stock Option (Right to Buy) | D — Disposition to the issuer | −666 | SEC filing |
Showing 8 of 10 rows
These tables describe filed transactions, not current holdings. Prices are shown as filed; a currency is added only when the filing's data names one. Amended and possible duplicate rows are left out of size comparisons and transaction groups.