Prime Medicine, Inc.
PRMEAs of the close on Sep 25, 2026
Price
$2.90
Market cap
$526M
P/E (diluted TTM)
—
The fourth quarter's per-share figure could not be confirmed from the annual report
EPS (TTM)
—
The fourth quarter's per-share figure could not be confirmed from the annual report
Dividend yield
—
Dividend records do not yet cover the latest payments
Figures shown here come from public SEC filings. Dates beside each section show the available history.
How Prime Medicine, Inc. Makes Money
Follow each dollar of revenue through to what shareholders keep.
From revenue to net income
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Source: Prime Medicine, Inc. — 10-K filed Mar 3, 2026
Financial Summary
Choose a year or quarter, compare it with the same period a year earlier, and open any row for its full filing history.
Loading financial history…
SEC filings supply these figures; updates after the dates shown are not included. This page includes 6 annual periods. The latest annual period ends Dec 31, 2025. The latest insider filing shown is dated Jun 8, 2026. The latest institutional report shown is dated Mar 31, 2026; other ownership filings may exist.
Ownership
Who holds the shares, as reported in SEC ownership filings.
Reported 13F positions
Each row shows what a filer reported for one date, not a current position. The link opens that filing.
| Filer | Report date | Shares | Value | Filing |
|---|---|---|---|---|
| ARK Investment Management LLC | 2026-03-31 | 6,246,827 | Not shown | SEC filing |
| CHELSEA COUNSEL CO | 2026-03-31 | 227,000 | Not shown | SEC filing |
| ROYAL BANK OF CANADA | 2026-03-31 | 9,254 | Not shown | SEC filing |
| CWM, LLC | 2026-03-31 | 33,811 | Not shown | SEC filing |
| OSAIC HOLDINGS, INC. | 2026-03-31 | 4,097 | Not shown | SEC filing |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 2026-03-31 | 134,800 | Not shown | SEC filing |
| Prime Capital Investment Advisors, LLC | 2026-03-31 | 12,945 | Not shown | SEC filing |
| DEUTSCHE BANK AG\ | 2026-03-31 | 157,440 | Not shown | SEC filing |
| Alphabet Inc. | 2026-03-31 | 16,562,498 | Not shown | SEC filing |
| AXQ CAPITAL, LP | 2026-03-31 | 36,742 | Not shown | SEC filing |
| Rafferty Asset Management, LLC | 2026-03-31 | 215,582 | Not shown | SEC filing |
| Fortitude Family Office, LLC | 2026-03-31 | 436 | Not shown | SEC filing |
| COMMONWEALTH EQUITY SERVICES, LLC | 2026-03-31 | 16,437 | Not shown | SEC filing |
| NOMURA HOLDINGS INC | 2026-03-31 | 24,823 | Not shown | SEC filing |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 2026-03-31 | 715,829 | Not shown | SEC filing |
| OPPENHEIMER & CO INC | 2026-03-31 | 33,656 | Not shown | SEC filing |
| PROFUND ADVISORS LLC | 2026-03-31 | 95,806 | Not shown | SEC filing |
| TWO SIGMA INVESTMENTS, LP | 2026-03-31 | 1,572,811 | Not shown | SEC filing |
| Casdin Capital, LLC | 2026-03-31 | 3,167,175 | Not shown | SEC filing |
| NATIONAL BANK OF CANADA /FI/ | 2026-03-31 | 10 | Not shown | SEC filing |
- Each value is checked against Prime Medicine, Inc.'s share prices from within about three months of its report date (insiders' Form 4 trades and the latest close).
- Value not shown for 20 rows: no share price from within three months of their report dates is on file, so they could not be checked.
120 filers have only one report here.
Unusually large insider trades
Each trade is compared with the other insider trades of the same kind in the same security among Prime Medicine, Inc.'s recent filings on file. Size alone is context, not a prediction or evidence of improper trading.
- 2023-05-22 · Alphabet Inc.: Larger than 29 of the 32 other insider sales of Common Stock on file. SEC filing
- 2023-05-15 · Alphabet Inc.: Larger than 31 of the 32 other insider sales of Common Stock on file. SEC filing
- 2023-05-09 · Alphabet Inc.: Larger than all 32 other insider sales of Common Stock on file. SEC filing
- 2023-05-08 · Alphabet Inc.: Larger than 30 of the 32 other insider sales of Common Stock on file. SEC filing
Independent insiders buying near the same time
- 2025-08-01–2025-08-01: 4 event(s) across 4 owner(s) — A cluster counts independent reporting owners that reported purchases within a set time. Co-filers and declared affiliates count once, and duplicate reports of the same event count once. ( filing , filing , filing , filing )
- 2025-05-20–2025-05-21: 3 event(s) across 3 owner(s) — A cluster counts independent reporting owners that reported purchases within a set time. Co-filers and declared affiliates count once, and duplicate reports of the same event count once. ( filing , filing , filing )
- 2024-02-15–2024-02-15: 3 event(s) across 3 owner(s) — A cluster counts independent reporting owners that reported purchases within a set time. Co-filers and declared affiliates count once, and duplicate reports of the same event count once. ( filing , filing , filing )
- 2022-10-24–2022-10-24: 4 event(s) across 4 owner(s) — A cluster counts independent reporting owners that reported purchases within a set time. Co-filers and declared affiliates count once, and duplicate reports of the same event count once. ( filing , filing , filing , filing )
Purchases & sales (open market or private)
| Security | Code | Price | Filing | |||
|---|---|---|---|---|---|---|
| 2025-08-01 | CRANDELL KEITH · 10% owner | Common Stock | P — Open market or private purchase | +3,030,300 | 3.30 | SEC filing |
| 2025-08-01 | NELSEN ROBERT · Director, 10% owner | Common Stock | P — Open market or private purchase | +3,030,300 | 3.30 | SEC filing |
| 2025-08-01 | Alphabet Inc. · 10% owner | Common Stock | P — Open market or private purchase | +1,500,000 | 3.30 | SEC filing |
| 2025-08-01 | ARCH Venture Fund XII, L.P. · 10% owner | Common Stock | P — Open market or private purchase | +3,030,300 | 3.30 | SEC filing |
| 2025-06-30 | Liu David R. · 10% owner | Common Stock | P — Open market or private purchase | +21,000 | 2.52 | SEC filing |
| 2025-06-23 | Liu David R. · 10% owner | Common Stock | P — Open market or private purchase | +21,000 | 2.16 | SEC filing |
| 2025-06-16 | Liu David R. · 10% owner | Common Stock | P — Open market or private purchase | +21,000 | 1.49 | SEC filing |
| 2025-06-11 | Liu David R. · 10% owner | Common Stock | P — Open market or private purchase | +21,000 | 1.60 | SEC filing |
Showing 8 of 20 rows
Grants, exercises, tax & gifts
| Security | Code | Filing | |||
|---|---|---|---|---|---|
| 2026-06-05 | Chung Wendy · Director | Stock Option (right to buy) | A — Grant, award, or other acquisition | +75,000 | SEC filing |
| 2026-06-05 | Foster-Cheek Kaye I · Director | Stock Option (right to buy) | A — Grant, award, or other acquisition | +75,000 | SEC filing |
| 2026-06-05 | Marrazzo Jeffrey D · Director | Stock Option (right to buy) | A — Grant, award, or other acquisition | +75,000 | SEC filing |
| 2026-06-05 | NELSEN ROBERT · Director, 10% owner | Stock Option (right to buy) | A — Grant, award, or other acquisition | +75,000 | SEC filing |
| 2026-06-05 | Schenkein David P · Director | Stock Option (right to buy) | A — Grant, award, or other acquisition | +75,000 | SEC filing |
| 2026-06-05 | Cahill Thomas · Director | Stock Option (right to buy) | A — Grant, award, or other acquisition | +75,000 | SEC filing |
| 2026-06-05 | Kelly Michael Aaron · Director | Stock Option (right to buy) | A — Grant, award, or other acquisition | +75,000 | SEC filing |
| 2026-04-16 | Makhni Svetlana Ni · Chief Financial Officer | Stock Option (right to buy) | A — Grant, award, or other acquisition | +800,000 | SEC filing |
Showing 8 of 27 rows
Other activity
| Security | Code | Filing | |||
|---|---|---|---|---|---|
| 2025-08-01 | Foster-Cheek Kaye I · Director | Stock Option (right to buy) | D — Disposition to the issuer | −9,006 | SEC filing |
| 2025-08-01 | LEE ANN L. · Chief Technical Officer | Stock Option (right to buy) | D — Disposition to the issuer | −180,995 | SEC filing |
| 2025-08-01 | Chung Wendy · Director | Stock Option (right to buy) | D — Disposition to the issuer | −39,062 | SEC filing |
| 2025-08-01 | Marrazzo Jeffrey D · Director | Stock Option (right to buy) | D — Disposition to the issuer | −250,000 | SEC filing |
| 2025-08-01 | Foster-Cheek Kaye I · Director | Stock Option (right to buy) | D — Disposition to the issuer | −13,510 | SEC filing |
| 2025-08-01 | Alenson Carman · See Remarks | Stock Option (right to buy) | D — Disposition to the issuer | −6,254 | SEC filing |
| 2025-08-01 | Reine Allan · Chief Executive Officer | Stock Option (right to buy) | D — Disposition to the issuer | −850,000 | SEC filing |
| 2025-08-01 | NELSEN ROBERT · Director, 10% owner | Stock Option (right to buy) | D — Disposition to the issuer | −45,000 | SEC filing |
Showing 8 of 10 rows
These tables describe filed transactions, not current holdings. Prices are shown as filed; a currency is added only when the filing's data names one. Amended and possible duplicate rows are left out of size comparisons and transaction groups.