Alnylam Pharmaceuticals, Inc.
ALNYAs of the close on Sep 25, 2026
Price
$255.96
Market cap
$34.2B
P/E (diluted TTM)
—
A per-share figure for one of the last four quarters is not shown, so no four-quarter total is given
EPS (TTM)
—
A per-share figure for one of the last four quarters is not shown, so no four-quarter total is given
Dividend yield
—
Dividend records do not yet cover the latest payments
Figures shown here come from public SEC filings. Dates beside each section show the available history.
How Alnylam Pharmaceuticals, Inc. Makes Money
Follow each dollar of revenue through to what shareholders keep.
From revenue to net income
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Financial Summary
Choose a year or quarter, compare it with the same period a year earlier, and open any row for its full filing history.
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SEC filings supply these figures; updates after the dates shown are not included. This page includes 18 annual periods. The latest annual period ends Dec 31, 2025. The latest insider filing shown is dated Jun 3, 2026. The latest institutional report shown is dated Mar 31, 2026; other ownership filings may exist.
Ownership
Who holds the shares, as reported in SEC ownership filings.
Reported 13F positions
Each row shows what a filer reported for one date, not a current position. The link opens that filing.
| Filer | Report date | Shares | Value | Filing |
|---|---|---|---|---|
| Sanctuary Advisors, LLC | 2026-03-31 | 5,839 | $1.93M | SEC filing |
| PEOPLES FINANCIAL SERVICES CORP. | 2026-03-31 | 50 | $16.5K | SEC filing |
| Front Row Advisors LLC | 2026-03-31 | 7 | $2.32K | SEC filing |
| Phillip James Consulting Co. | 2026-03-31 | 3 | $1K | SEC filing |
| Louisiana State Employees Retirement System | 2026-03-31 | 8,700 | $2.88M | SEC filing |
| OVERSEA-CHINESE BANKING Corp Ltd | 2026-03-31 | 973 | $322K | SEC filing |
| CERTUITY, LLC | 2026-03-31 | 654 | $217K | SEC filing |
| Quadrature Capital Ltd | 2026-03-31 | 85,241 | $28.2M | SEC filing |
| Plante Moran Financial Advisors, LLC | 2026-03-31 | 635 | $210K | SEC filing |
| TD Capital Management LLC | 2026-03-31 | 23 | $7.61K | SEC filing |
| PROFUND ADVISORS LLC | 2026-03-31 | 14,647 | $4.85M | SEC filing |
| Vermillion Wealth Management, Inc. | 2026-03-31 | 3 | $993 | SEC filing |
| Caprock Group, LLC | 2026-03-31 | 1,190 | $394K | SEC filing |
| CANADA LIFE ASSURANCE Co | 2026-03-31 | 57,255 | Not shown | SEC filing |
| OPPENHEIMER ASSET MANAGEMENT INC. | 2026-03-31 | 19,842 | $6.57M | SEC filing |
| Anchor Investment Management, LLC | 2026-03-31 | 2,819 | $933K | SEC filing |
| Advisory Services Network, LLC | 2026-03-31 | 6,314 | $2.09M | SEC filing |
| SG Americas Securities, LLC | 2026-03-31 | 55,060 | Not shown | SEC filing |
| CAPTRUST FINANCIAL ADVISORS | 2026-03-31 | 12,503 | $4.14M | SEC filing |
| Assenagon Asset Management S.A. | 2026-03-31 | 128,896 | $42.6M | SEC filing |
- Each value is checked against Alnylam Pharmaceuticals, Inc.'s share prices from within about three months of its report date (insiders' Form 4 trades and the latest close).
- Value not shown for 2 rows: the filed value is about 1,000 times too small for the share count at Alnylam Pharmaceuticals, Inc.'s share price.
120 filers have only one report here.
Unusually large insider trades
Each trade is compared with the other insider trades of the same kind in the same security among Alnylam Pharmaceuticals, Inc.'s recent filings on file. Size alone is context, not a prediction or evidence of improper trading.
- 2026-06-01 · PYOTT DAVID E I: Larger than 186 of the 196 other insider sales of Common Stock on file. SEC filing
- 2026-06-01 · PYOTT DAVID E I: Larger than 187 of the 196 other insider sales of Common Stock on file. SEC filing
- 2026-06-01 · PYOTT DAVID E I: Larger than 180 of the 196 other insider sales of Common Stock on file. SEC filing
- 2026-04-06 · McLaughlin Melissa: Larger than 179 of the 196 other insider sales of Common Stock on file. SEC filing
- 2026-04-06 · McLaughlin Melissa: Larger than 178 of the 196 other insider sales of Common Stock on file. SEC filing
- 2026-03-04 · Greenstreet Yvonne: Larger than 182 of the 196 other insider sales of Common Stock on file. SEC filing
- 2026-03-04 · Poulton Jeffrey V.: Larger than 177 of the 196 other insider sales of Common Stock on file. SEC filing
- 2026-03-02 · Greenstreet Yvonne: Larger than 189 of the 196 other insider sales of Common Stock on file. SEC filing
- 2026-03-02 · Greenstreet Yvonne: Larger than 188 of the 196 other insider sales of Common Stock on file. SEC filing
- 2026-03-02 · Greenstreet Yvonne: Larger than 184 of the 196 other insider sales of Common Stock on file. SEC filing
- 2026-02-27 · Garg Pushkal: Larger than 185 of the 196 other insider sales of Common Stock on file. SEC filing
- 2026-02-27 · Garg Pushkal: Larger than 181 of the 196 other insider sales of Common Stock on file. SEC filing
- 2026-02-27 · Garg Pushkal: Larger than 195 of the 196 other insider sales of Common Stock on file. SEC filing
- 2026-02-17 · Fitzgerald Kevin Joseph: Larger than 192 of the 196 other insider sales of Common Stock on file. SEC filing
- 2026-02-13 · Greenstreet Yvonne: Larger than all 196 other insider sales of Common Stock on file. SEC filing
- 2026-02-13 · Fitzgerald Kevin Joseph: Larger than 190 of the 196 other insider sales of Common Stock on file. SEC filing
- 2026-02-13 · Garg Pushkal: Larger than 193 of the 196 other insider sales of Common Stock on file. SEC filing
- 2026-02-13 · Tanguler Tolga: Larger than 190 of the 196 other insider sales of Common Stock on file. SEC filing
- 2026-02-13 · Poulton Jeffrey V.: Larger than 193 of the 196 other insider sales of Common Stock on file. SEC filing
- 2026-01-12 · Greenstreet Yvonne: Larger than 183 of the 196 other insider sales of Common Stock on file. SEC filing
Purchases & sales (open market or private)
| Security | Code | Price | Filing | |||
|---|---|---|---|---|---|---|
| 2026-06-01 | PYOTT DAVID E I · Director | Common Stock | S — Open market or private sale | −921 | 297.71 | SEC filing |
| 2026-06-01 | PYOTT DAVID E I · Director | Common Stock | S — Open market or private sale | −17 | 302.65 | SEC filing |
| 2026-06-01 | PYOTT DAVID E I · Director | Common Stock | S — Open market or private sale | −495 | 300.72 | SEC filing |
| 2026-06-01 | PYOTT DAVID E I · Director | Common Stock | S — Open market or private sale | −1,222 | 299.87 | SEC filing |
| 2026-06-01 | PYOTT DAVID E I · Director | Common Stock | S — Open market or private sale | −1,175 | 298.91 | SEC filing |
| 2026-04-06 | McLaughlin Melissa · Chief Human Resources Officer | Common Stock | S — Open market or private sale | −56 | 320.14 | SEC filing |
| 2026-04-06 | McLaughlin Melissa · Chief Human Resources Officer | Common Stock | S — Open market or private sale | −829 | 330.46 | SEC filing |
| 2026-04-06 | McLaughlin Melissa · Chief Human Resources Officer | Common Stock | S — Open market or private sale | −199 | 333.94 | SEC filing |
Showing 8 of 10 rows
Grants, exercises, tax & gifts
| Security | Code | Filing | |||
|---|---|---|---|---|---|
| 2026-06-01 | PYOTT DAVID E I · Director | Common Stock | M — Exercise or conversion of derivative security | +3,830 | SEC filing |
| 2026-06-01 | PYOTT DAVID E I · Director | Stock Option (Right to Buy) | M — Exercise or conversion of derivative security | −3,830 | SEC filing |
| 2026-06-01 | Cravatt Benjamin · Director | Stock Option (Right to Buy) | A — Grant, award, or other acquisition | +4,393 | SEC filing |
| 2026-05-20 | Arbuckle Stuart A · Director | Common Stock | A — Grant, award, or other acquisition | +671 | SEC filing |
| 2026-05-20 | PYOTT DAVID E I · Director | Stock Option (Right to Buy) | A — Grant, award, or other acquisition | +1,441 | SEC filing |
| 2026-05-20 | Reitan Colleen F · Director | Common Stock | A — Grant, award, or other acquisition | +671 | SEC filing |
| 2026-05-20 | HAMBURG MARGARET A · Director | Common Stock | A — Grant, award, or other acquisition | +671 | SEC filing |
| 2026-05-20 | KELLOGG PETER N · Director | Common Stock | A — Grant, award, or other acquisition | +671 | SEC filing |
Showing 8 of 20 rows
These tables describe filed transactions, not current holdings. Prices are shown as filed; a currency is added only when the filing's data names one. Amended and possible duplicate rows are left out of size comparisons and transaction groups.